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@MISC{Zhao:1034519,
author = {Zhao, Ling and Zilles, Karl and Palomero-Gallagher, Nicola
and Puchades, Maja A.},
title = {{R}egional and laminar distribution of silver stained cell
bodies in the rat brain (v2)},
publisher = {EBRAINS},
reportid = {FZJ-2024-07282},
year = {2024},
abstract = {Classical mapping studies relied on the analysis of
histologically processed sections from formalin-fixed brains
for the identification of borders between cortical areas or
of the boundaries of subcortical nuclei. Differences in the
regional and laminar distribution patterns of
neurotransmitter receptors are known to complement and
extend the insights into the structural organization of the
brain, which are provided by cytoarchitectonic observations
alone. Since the method of quantitative in vitro receptor
autoradiography requires processing of unfixed, shock frozen
brains, we here present a modification of a silver cell body
histological staining which can be applied to cryosections
neighbouring those destined to labelling of receptors. The
histological staining resembles a Nissl staining, but yields
a higher contrast between cell bodies and neuropil, and can
also be used for quantitative approaches to
cytoarchitectonic mapping. The present dataset provides
high-resolution digitized images of coronal sections through
the rat brain that were processed for the visualization of
cell bodies, and which complement a series processed for the
visualization of 19 different receptor binding sites from
multiple neurotransmitter systems. We also provide
information about image data registration to the Waxholm
Sprague Dawley rat brain atlas.},
keywords = {Neuroscience (Other)},
cin = {INM-1},
cid = {I:(DE-Juel1)INM-1-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525) / HBP SGA2 - Human Brain Project Specific Grant
Agreement 2 (785907) / HBP SGA3 - Human Brain Project
Specific Grant Agreement 3 (945539) / EBRAINS 2.0 - EBRAINS
2.0: A Research Infrastructure to Advance Neuroscience and
Brain Health (101147319)},
pid = {G:(DE-HGF)POF4-5251 / G:(EU-Grant)785907 /
G:(EU-Grant)945539 / G:(EU-Grant)101147319},
typ = {PUB:(DE-HGF)32},
doi = {10.25493/D8NF-B83},
url = {https://juser.fz-juelich.de/record/1034519},
}