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| 001 | 1037823 | ||
| 005 | 20250310131243.0 | ||
| 024 | 7 | _ | |a 10.3390/md23020053 |2 doi |
| 024 | 7 | _ | |a 10.34734/FZJ-2025-00975 |2 datacite_doi |
| 024 | 7 | _ | |a 39997177 |2 pmid |
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| 041 | _ | _ | |a English |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Aurino, Elena |0 P:(DE-HGF)0 |b 0 |e First author |
| 245 | _ | _ | |a Functional and Bioactive Benefits of Selected Microalgal Hydrolysates Assessed In Silico and In Vitro |
| 260 | _ | _ | |a Basel |c 2025 |b MDPI |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1738234738_29869 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a Dear library team, the grant under which that publication was done is theNORTH-WEST EUROPE INTERREG, grant number NWE 639 as part of the IDEA+ project |
| 520 | _ | _ | |a BIOPEP-UWM, a peptide database, contains 5128 peptides from a myriad of resources. Five listed peptides are Angiotensin-I-converting enzyme (ACE-1; EC3.4.15.1) inhibitory peptides derived from a red alga, while two from Chlorella vulgaris have anti-cancer and antioxidative bioactivities. Herein, we describe a process combining hydrolysis with two enzymes, Alcalase and Viscozyme, and filtration to generate protein-rich, bioactive peptide-containing hydrolysates from mixed species of Chlorella sp. and Scenedesmus sp. The potential of generated algal hydrolysates to act as food ingredients was determined by assessment of their techno-functional (foaming, emulsification, solubility, water holding, and oil holding capacity) properties. Bioactive screening of hydrolysates in vitro combined with mass spectrometry (MS) and in silico predictions identified bioactive and functional hydrolysates and six novel peptides. Peptides derived from Chlorella mix have the sequences YDYIGNNPAKGGLF and YIGNNPAKGGLF with predicted anti-inflammatory (medium confidence) and umami potential. Peptides from Scenedesmus mix have sequences IEWYGPDRPKFL, RSPTGEIIFGGETM, TVQIPGGERVPFLF, and IEWYGPDRPKFLGPF with predicted anti-inflammatory, anti-diabetic, and umami attributes. Such microalgal hydrolysates could provide essential amino acids to consumers as well as tertiary health benefits to improve human global health. |
| 536 | _ | _ | |a 2171 - Biological and environmental resources for sustainable use (POF4-217) |0 G:(DE-HGF)POF4-2171 |c POF4-217 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to DataCite |
| 700 | 1 | _ | |a Mora, Leticia |0 P:(DE-HGF)0 |b 1 |
| 700 | 1 | _ | |a Marzocchella, Antonio |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Kuchendorf , Christina M. |0 ORCID |b 3 |
| 700 | 1 | _ | |a Ackermann, Bärbel |0 P:(DE-HGF)0 |b 4 |
| 700 | 1 | _ | |a Hayes, Maria |0 P:(DE-HGF)0 |b 5 |e Corresponding author |
| 770 | _ | _ | |a Marine Algal Biotechnology and Applications |
| 773 | _ | _ | |a 10.3390/md23020053 |0 PERI:(DE-600)2175190-0 |n 2 |p 53 |t Marine drugs |v 23 |y 2025 |x 1660-3397 |
| 856 | 4 | _ | |u https://www.mdpi.com/1660-3397/23/2/53# |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/1037823/files/marinedrugs-23-00053.pdf |y OpenAccess |
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| 910 | 1 | _ | |a Food BioSciences, Teagasc Food Research Centre |0 I:(DE-HGF)0 |b 0 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Dipartimento di Ingegneria Chimica, dei Materiali, e della Produzione Industriale, Università degli Studi di Napoli ‘Federico II’ |0 I:(DE-HGF)0 |b 0 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Instituto de Agroquímica y Tecnología de Alimentos (CSIC), |0 I:(DE-HGF)0 |b 1 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Dipartimento di Ingegneria Chimica, dei Materiali, e della Produzione Industriale, Università degli Studi di Napoli ‘Federico II’ |0 I:(DE-HGF)0 |b 2 |6 P:(DE-HGF)0 |
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| 910 | 1 | _ | |a Institute of Bio- and Geosciences, IBG-2—Plant Sciences Forschungszentrum Jülich GmbH, Wilhelm-Johnen-Str., 52428 Jülich, Germany |0 I:(DE-HGF)0 |b 3 |6 ORCID |
| 910 | 1 | _ | |a Stadt Erftstadt, Stabsstelle Klimaschutz, Holzdamm 10, 50374 Erftstadt, Germany |0 I:(DE-HGF)0 |b 4 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Food BioSciences, Teagasc Food Research Centre, Ashtown, D15 DY05 Dublin, Ireland |0 I:(DE-HGF)0 |b 5 |6 P:(DE-HGF)0 |
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