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@ARTICLE{Li:1040294,
author = {Li, Xuan and Eickhoff, Simon B. and Weis, Susanne},
title = {{S}timulus {S}election {I}nfluences {P}rediction of
{I}ndividual {P}henotypes in {N}aturalistic {C}onditions},
journal = {Human brain mapping},
volume = {46},
number = {3},
issn = {1065-9471},
address = {New York, NY},
publisher = {Wiley-Liss},
reportid = {FZJ-2025-01826},
pages = {e70164},
year = {2025},
note = {Funding: This work was supported by European Union's
Horizon 2020 Research and Innovation Programme (945539; HBP
SGA3) and Deutsche Forschungsgemeinschaft (491111487).},
abstract = {While the use of naturalistic stimuli such as movie clips
for understanding individual differences and
brain–behaviour relationships attracts increasing
interest, the influence of stimulus selection remains
largely unclear. By using machine learning to predict
individual traits (phenotypes) from brain activity evoked
during various movie clips, we show that different movie
stimuli can result in distinct prediction performances. In
brain regions related to lower-level processing of the
stimulus, prediction to a certain degree benefits from
stronger synchronisation of brain activity across subjects.
By contrast, better predictions in frontoparietal brain
regions are mainly associated with larger inter-subject
variability. Furthermore, we demonstrate that while movie
clips with rich social content in general achieve better
predictions, the importance of specific movie features for
prediction highly depends on the phenotype under
investigation. Overall, our findings underscore the
importance of careful stimulus selection and provide novel
insights into stimulus selection for phenotype prediction in
naturalistic conditions, opening new avenues for future
research.},
cin = {INM-7},
ddc = {610},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525) / 5252 - Brain Dysfunction and Plasticity
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251 / G:(DE-HGF)POF4-5252},
typ = {PUB:(DE-HGF)16},
pubmed = {39960115},
UT = {WOS:001422492000001},
doi = {10.1002/hbm.70164},
url = {https://juser.fz-juelich.de/record/1040294},
}