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@ARTICLE{Paquola:1040671,
      author       = {Paquola, Casey and Garber, Margaret and Frässle, Stefan
                      and Royer, Jessica and Zhou, Yigu and Tavakol, Shahin and
                      Rodriguez-Cruces, Raul and Cabalo, Donna Gift and Valk,
                      Sofie and Eickhoff, Simon B. and Margulies, Daniel S. and
                      Evans, Alan and Amunts, Katrin and Jefferies, Elizabeth and
                      Smallwood, Jonathan and Bernhardt, Boris C.},
      title        = {{T}he architecture of the human default mode network
                      explored through cytoarchitecture, wiring and signal flow},
      journal      = {Nature neuroscience},
      volume       = {28},
      number       = {3},
      issn         = {1097-6256},
      address      = {New York, NY},
      publisher    = {Nature America},
      reportid     = {FZJ-2025-01998},
      pages        = {654 - 664},
      year         = {2025},
      abstract     = {The default mode network (DMN) is implicated in many
                      aspects of complex thought and behavior. Here, we leverage
                      postmortem histology and in vivo neuroimaging to
                      characterize the anatomy of the DMN to better understand its
                      role in information processing and cortical communication.
                      Our results show that the DMN is cytoarchitecturally
                      heterogenous, containing cytoarchitectural types that are
                      variably specialized for unimodal, heteromodal and
                      memory-related processing. Studying diffusion-based
                      structural connectivity in combination with
                      cytoarchitecture, we found the DMN contains regions
                      receptive to input from sensory cortex and a core that is
                      relatively insulated from environmental input. Finally,
                      analysis of signal flow with effective connectivity models
                      showed that the DMN is unique amongst cortical networks in
                      balancing its output across the levels of sensory
                      hierarchies. Together, our study establishes an anatomical
                      foundation from which accounts of the broad role the DMN
                      plays in human brain function and cognition can be
                      developed.},
      cin          = {INM-7 / INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-7-20090406 / I:(DE-Juel1)INM-1-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525) / 5252 - Brain Dysfunction and Plasticity
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251 / G:(DE-HGF)POF4-5252},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {39875581},
      UT           = {WOS:001407563400001},
      doi          = {10.1038/s41593-024-01868-0},
      url          = {https://juser.fz-juelich.de/record/1040671},
}