% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Meiner:1041407,
      author       = {Meißner, Julius Nicolai and Neuneier, Janina and
                      Bartzokis, Iason and Rehm, Mathias and Al-Hayali, Ahmad and
                      Müller, Marcus and Paus, Sebastian and Limmroth, Volker and
                      Fink, Gereon R. and Petzold, Gabor C. and Nitsch, Louisa},
      title        = {{I}ncrease of nitrous oxide-induced neurological disorders
                      – a {G}erman multicenter experience},
      journal      = {Neurological research and practice},
      volume       = {7},
      number       = {1},
      issn         = {2524-3489},
      address      = {[London]},
      publisher    = {BioMed Central},
      reportid     = {FZJ-2025-02235},
      pages        = {3},
      year         = {2025},
      note         = {FundingThis research received no specific grant from any
                      funding agency in thepublic, commercial, or not-for-profit
                      sectors.Open Access funding enabled and organized by Projekt
                      DEAL.},
      abstract     = {BackgroundNitrous oxide (N₂O), commonly known as laughing
                      gas, is widely recognized for its anesthetic and analgesic
                      effects, and is frequently used in medical contexts.
                      However, its misuse can lead to significant neurological
                      complications, which are often under-recognized in clinical
                      practice. Recent data on such cases in Germany are rare. We
                      here report the spectrum of neurological complications
                      associated with the recreational use of N₂O, as
                      encountered in German neurology centers.MethodsWe
                      retrospectively analyzed of 23 cases presenting with
                      neurological symptoms following N₂O abuse between July
                      2020 and August 2024 across five neurology departments in
                      Germany. Data were collected on patient demographics,
                      clinical manifestations, diagnostic findings, and treatment
                      approaches.ResultsOver the last four years the number of
                      cases increased. Clinical presentations primarily included
                      neuropathy, found in all patients, along with myelopathy.
                      The most common symptoms were sensory loss, ataxia, and
                      motor deficits.ConclusionOur data suggest that N₂O abuse
                      is on the rise in Germany. Further initiatives are warranted
                      to raise awareness among users, healthcare and
                      professionals.},
      cin          = {INM-3},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-3-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {39815374},
      UT           = {WOS:001398048900001},
      doi          = {10.1186/s42466-024-00361-0},
      url          = {https://juser.fz-juelich.de/record/1041407},
}