%0 Conference Paper
%A Ceccacci, Silvia
%A Vicente Porres, Jose Angel
%A Rio Grela, Nerea
%A Calmet, Hadrien
%A Gargallo Peiro, Abel
%A Rigaut, Clement
%A Haut, Benoit
%A Houzeaux, Guillaume
%A Eguzkitza, Ane Beatriz
%T Computational Modeling of Particles Fate in Nasal Drug Treatments
%V 69
%C Jülich
%I Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag
%M FZJ-2025-02478
%B Schriften des Forschungszentrums Jülich IAS Series
%P 154 - 157
%D 2025
%< Proceedings of the 35th Parallel CFD International Conference 2024
%X The present work is one of the three pieces (upper airways, lower conductive and respiratory zones) of a digital twin lung model developed by the Physical and Numerical Modelling research group of the CASE department at the Barcelona Supercomputing Center (BSC). In this study, we focus on the upper airways, and we present a computational model to analyze the fate of particles in nasal drug treatments. By integrating fluid dynamics with particle transport algorithms, the computational model, implemented in the in-house code Alya, aims at predicting the particles behavior, from their interactions with the nasal cavity walls considering mucus layer, to their deposition and ultimately their fate once deposited. This work is framed within the project DREAMS: Particle Deposition Computational Model for ChildREn Airways with Mucus Surface.
%B 35th Parallel CFD International Conference 2024
%C 2 Sep 2024 - 4 Sep 2024, Bonn (Germany)
Y2 2 Sep 2024 - 4 Sep 2024
M2 Bonn, Germany
%F PUB:(DE-HGF)8 ; PUB:(DE-HGF)7
%9 Contribution to a conference proceedingsContribution to a book
%R 10.34734/FZJ-2025-02478
%U https://juser.fz-juelich.de/record/1042262