TY  - CONF
AU  - Ceccacci, Silvia
AU  - Vicente Porres, Jose Angel
AU  - Rio Grela, Nerea
AU  - Calmet, Hadrien
AU  - Gargallo Peiro, Abel
AU  - Rigaut, Clement
AU  - Haut, Benoit
AU  - Houzeaux, Guillaume
AU  - Eguzkitza, Ane Beatriz
TI  - Computational Modeling of Particles Fate in Nasal Drug Treatments
VL  - 69
CY  - Jülich
PB  - Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag
M1  - FZJ-2025-02478
T2  - Schriften des Forschungszentrums Jülich IAS Series
SP  - 154 - 157
PY  - 2025
AB  - The present work is one of the three pieces (upper airways, lower conductive and respiratory zones) of a digital twin lung model developed by the Physical and Numerical Modelling research group of the CASE department at the Barcelona Supercomputing Center (BSC). In this study, we focus on the upper airways, and we present a computational model to analyze the fate of particles in nasal drug treatments. By integrating fluid dynamics with particle transport algorithms, the computational model, implemented in the in-house code Alya, aims at predicting the particles behavior, from their interactions with the nasal cavity walls considering mucus layer, to their deposition and ultimately their fate once deposited. This work is framed within the project DREAMS: Particle Deposition Computational Model for ChildREn Airways with Mucus Surface.
T2  - 35th Parallel CFD International Conference 2024
CY  - 2 Sep 2024 - 4 Sep 2024, Bonn (Germany)
Y2  - 2 Sep 2024 - 4 Sep 2024
M2  - Bonn, Germany
LB  - PUB:(DE-HGF)8 ; PUB:(DE-HGF)7
DO  - DOI:10.34734/FZJ-2025-02478
UR  - https://juser.fz-juelich.de/record/1042262
ER  -