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@ARTICLE{Hong:1043249,
      author       = {Hong, Suk-Min and Choi, Chang-Hoon and Felder, Jörg and
                      Shah, N. Jon},
      title        = {{N}ovel 1 {H}/ 19 {F} double‐tuned coil using an
                      asymmetrical butterfly coil},
      journal      = {Medical physics},
      volume       = {52},
      number       = {7},
      issn         = {0094-2405},
      address      = {Hoboken, NJ},
      publisher    = {Wiley},
      reportid     = {FZJ-2025-02799},
      pages        = {17890},
      year         = {2025},
      abstract     = {Background: Fluorine-19 (19F) magnetic resonance imaging
                      (MRI) is a non-invasive imaging tool for the targeted
                      application of fluorinated agents, such as cell tracking,
                      and for the demonstration of oximetry. However, as the SNR
                      of 19F is significantly weaker than that of proton (1H)
                      imaging, the 19F coil must be combined with 1H coils for
                      anatomical co-registration and B0 shimming. This is
                      difficult due to the strong coupling between the coils when
                      they are in proximity, and is problematic since the Larmor
                      frequency of 19F is $94\%$ that of 1H, further increasing
                      the potential for coupling between the 1H and 19F
                      elements.Purpose: Conventional double-tuned coil methods
                      tend to generate loss compared to single-tuned reference
                      coils. The asymmetrical butterfly coil has a split resonance
                      peak, which can cover frequencies of 1H and 19F without
                      losses arising from lossy traps or switching circuits. In
                      this study, the use of an asymmetrical butterfly coil was
                      evaluated for 1H/19F applications.Methods: To increase
                      quadrature efficiency at both the 1H and 19F frequencies,
                      the left and right loops of the butterfly coil were tuned
                      asymmetrically. The coil's tuning and performance were
                      evaluated in simulations and MR measurements, and the
                      results were compared to a dimension-matched single-tuned
                      loop coil.Results: The split resonance peak of the
                      asymmetrical butterfly coil successfully spanned the 19F to
                      1H frequency. It operated with higher quadrature efficiency
                      at both 1H and 19F frequencies and demonstrated superior
                      receive sensitivity and SNR compared to the
                      dimension-matched single-tuned loop coil.Conclusions: The
                      split resonance peak of the asymmetrical butterfly coil
                      supported both 1H and 19F frequencies, delivering a higher
                      SNR than that of the single-tuned loop coil. Since the
                      asymmetrical butterfly coil can cover ¹H and ¹⁹F
                      frequencies without loss and provides higher efficiency than
                      the reference single-tuned coil, it can be effectively
                      utilized for ¹H/¹⁹F MRI applications.},
      cin          = {INM-4},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-4-20090406},
      pnm          = {5253 - Neuroimaging (POF4-525) / DFG project
                      G:(GEPRIS)491111487 - Open-Access-Publikationskosten / 2025
                      - 2027 / Forschungszentrum Jülich (OAPKFZJ) (491111487)},
      pid          = {G:(DE-HGF)POF4-5253 / G:(GEPRIS)491111487},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.1002/mp.17890},
      url          = {https://juser.fz-juelich.de/record/1043249},
}