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@INPROCEEDINGS{Lin:1043687,
author = {Lin, Feng and Albantakis, Laura and Noppari, Tuomo and
Santavirta, Severi and Brandi, Marie-Luise and Sun, Lihua
and Lukkarinen, Lasse and Tani, Pekka and Salmi, Juha and
Nummenmaa, Lauri and Dukart, Jürgen and Schilbach, Leonhard
and Lahnakoski, Juha},
title = {{R}educed inter-subject functional connectivity during
movies in autism: {R}eplicability across cross-national
f{MRI} datasets},
reportid = {FZJ-2025-02985},
year = {2025},
abstract = {Autism is a neurodevelopmental condition characterized by
impairedsocial communication and interaction, restricted
interests, stereotypedbehaviors, and altered sensory
responses to external stimuli (AmericanPsychiatric
Association, 2013). Many autistic individuals
withoutintellectual impairment perform well in controlled
tasks, such asrecognizing emotional facial expressions
(Keating et al., 2023), but theirperformance often declines
in naturalistic settings requiring implicit socialprocessing
(Van de Cruys et al., 2014). Functional magnetic
resonanceimaging (fMRI), during naturalistic stimuli, such
as movies, has proveneffective for examining social brain
activity (Finn et al., 2020). Intersubjectfunctional
connectivity (ISFC) measures the interregionalconnectivity
across individuals, by separating the shared and
stimulusdrivencomponent of fMRI responses from intrinsic
brain activity andnoise (Simony et al., 2016). Previous
findings suggest idiosyncratic ISFCpatterns in autistic
individuals (Bolton et al., 2018), but the preciseregional
differences remain unclear and may vary across movie
segments.Addressing the reproducibility crisis in
neuroimaging (Kelly $\&$ Hoptman,2022), cross-center
experiment design can validate the generalizability
offindings. This study aimed to investigate the difference
of inter-subjectfunctional connectivity between autistic
individuals and neurotypicalcontrols and to evaluate their
replication across datasets.},
month = {Jun},
date = {2025-06-24},
organization = {OHBM Annual Meeting, Brisbane
(Australia), 24 Jun 2025 - 28 Jun 2025},
subtyp = {After Call},
cin = {INM-7},
cid = {I:(DE-Juel1)INM-7-20090406},
pnm = {5251 - Multilevel Brain Organization and Variability
(POF4-525)},
pid = {G:(DE-HGF)POF4-5251},
typ = {PUB:(DE-HGF)24},
doi = {10.34734/FZJ-2025-02985},
url = {https://juser.fz-juelich.de/record/1043687},
}