% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Jiang:1045525,
      author       = {Jiang, Lin and Genon, Sarah and Ye, Jiayu and Zhu, Yan and
                      Wang, Guangying and He, Runyang and Valdes-Sosa, Pedro A.
                      and Wan, Feng and Yao, Dezhong and Eickhoff, Simon B. and
                      Dong, Debo and Li, Fali and Xu, Peng},
      title        = {{G}ene transcription, neurotransmitter, and neurocognition
                      signatures of brain structural-functional coupling
                      variability},
      journal      = {Nature Communications},
      volume       = {16},
      number       = {1},
      issn         = {2041-1723},
      address      = {[London]},
      publisher    = {Springer Nature},
      reportid     = {FZJ-2025-03530},
      pages        = {7623},
      year         = {2025},
      abstract     = {The relationship between brain structure and function,
                      known as structural-functional coupling (SFC), is highly
                      dynamic. However, the temporal variability of this
                      relationship, referring to the fluctuating extent to which
                      functional profiles interact with anatomy over time, remains
                      poorly elucidated. Here, we propose a framework to quantify
                      SFC temporal variability and determine its neurocognitive
                      map, genetic architecture, and neurochemical basis in 1206
                      healthy human participants. Results reveal regional
                      heterogeneity in SFC variability and a composite emotion
                      dimension co-varying with variability patterns involving the
                      dorsal attention, somatomotor, and visual networks. The
                      transcriptomic signatures of SFC variability are enriched in
                      synapse- and cell cycle-related biological processes and
                      implicated in emotion-related disorders. Moreover, regional
                      densities of serotonin, glutamate, γ-aminobutyric acid, and
                      opioid systems are predictive of SFC variability across the
                      cortex. Collectively, SFC variability mapping provides a
                      biologically plausible framework for understanding how SFC
                      fluctuates over time to support macroscale neurocognitive
                      specialization.},
      cin          = {INM-7},
      ddc          = {500},
      cid          = {I:(DE-Juel1)INM-7-20090406},
      pnm          = {5251 - Multilevel Brain Organization and Variability
                      (POF4-525)},
      pid          = {G:(DE-HGF)POF4-5251},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {40817330},
      UT           = {WOS:001551663400044},
      doi          = {10.1038/s41467-025-63000-5},
      url          = {https://juser.fz-juelich.de/record/1045525},
}