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@ARTICLE{Schilbach:10456,
author = {Schilbach, L. and Wilms, M. and Eickhoff, S. B. and
Romanzetti, S. and Tepest, R. and Bente, G. and Shah, J. N.
and Fink, G. R. and Vogeley, K.},
title = {{M}inds {M}ade for {S}haring: {I}nitiating {J}oint
{A}ttention {R}ecruits {R}eward-related {N}eurocircuitry},
journal = {Journal of cognitive neuroscience},
volume = {22},
issn = {0898-929X},
address = {Cambridge, Mass.},
publisher = {MIT Pr. Journals},
reportid = {PreJuSER-10456},
pages = {2702 - 2715},
year = {2010},
note = {We thank all the colleagues in the MR and Cognitive
Neurology group at the Research Centre Julich for their
support. In particular, we would like to thank Barbara
Elghahwagi and Dorothe Krug for their help during fMRI data
acquisition. L. S. is also grateful to Nicole David, Shaun
Gallagher, Stefan Heim, Rudiger Ilg, Bojana Kuzmanovic, Anna
Rotarska-Jagiela, Tobias Schlicht, David Sharp, and Ralph
Weidner for their helpful advice and stimulating
comments.The study was supported by the German Ministry for
Education and Research, the Volkswagen Foundation, and by a
personal grant to L. S. by the "Kompetenzzentrum NeuroNRW"
at the Ministry of Innovation, Science, Research and
Technology of North-Rhine Westfalia, Germany.},
abstract = {The ability and motivation to share attention is a unique
aspect of human cognition. Despite its significance, the
neural basis remains elusive. To investigate the neural
correlates of joint attention, we developed a novel,
interactive research paradigm in which participants' gaze
behavior--as measured by an eye tracking device--was used to
contingently control the gaze of a computer-animated
character. Instructed that the character on screen was
controlled by a real person outside the scanner, 21
participants interacted with the virtual other while
undergoing fMRI. Experimental variations focused on leading
versus following the gaze of the character when fixating one
of three objects also shown on the screen. In concordance
with our hypotheses, results demonstrate, firstly, that
following someone else's gaze to engage in joint attention
resulted in activation of anterior portion of medial
prefrontal cortex (MPFC) known to be involved in the
supramodal coordination of perceptual and cognitive
processes. Secondly, directing someone else's gaze toward an
object activated the ventral striatum which--in light of
ratings obtained from participants--appears to underlie the
hedonic aspects of sharing attention. The data, therefore,
support the idea that other-initiated joint attention relies
upon recruitment of MPFC previously related to the "meeting
of minds." In contrast, self-initiated joint attention leads
to a differential increase of neural activity in
reward-related brain areas, which might contribute to the
uniquely human motivation to engage in the sharing of
experiences.},
keywords = {Adolescent / Adult / Analysis of Variance / Attention:
physiology / Brain Mapping / Eye Movements: physiology /
Humans / Image Processing, Computer-Assisted / Magnetic
Resonance Imaging / Male / Motivation: physiology / Nerve
Net: physiology / Photic Stimulation / Prefrontal Cortex:
physiology / Reward / J (WoSType)},
cin = {INM-2 / INM-3 / INM-4 / JARA-BRAIN},
ddc = {400},
cid = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-3-20090406 /
I:(DE-Juel1)INM-4-20090406 / $I:(DE-82)080010_20140620$},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89572 - (Dys-)function and Plasticity (POF2-89572)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89572},
shelfmark = {Neurosciences / Psychology, Experimental},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:19929761},
UT = {WOS:000281129400003},
doi = {10.1162/jocn.2009.21401},
url = {https://juser.fz-juelich.de/record/10456},
}