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@ARTICLE{Pourshahidi:1047250,
      author       = {Pourshahidi, Ali Mohammad and Jeong, Jae Chan and Krause,
                      Hans-Joachim and Hong, Hyo Bong},
      title        = {{M}agnetic nanoparticle spectroscopy for multiplex
                      detection: {I}nsights from frequency mixing magnetic
                      detection},
      journal      = {Sensors and actuators / A},
      volume       = {396},
      issn         = {0924-4247},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {FZJ-2025-04181},
      pages        = {117095 -},
      year         = {2025},
      abstract     = {Magnetic nanoparticles (MNPs) have shown promising
                      applications in the field of biomedical sciences.
                      Subsequently, various types of Magnetic Particle
                      Spectroscopy (MPS) have been proposed for quantitative and
                      qualitative analysis of MNPs. Among the various functions of
                      MPS proposed so far, the development of technology that can
                      analyze multiplex detection of different types of MNPs has
                      attracted due to the expansion of various application
                      fields. For example, the technology can be applied to
                      enhance efficiency in biosensors, process analysis in MNP
                      manufacturing, and measurement of various diseases in MPI.
                      In our investigation, we perform a comparative study of
                      different commercially available MNPs for use in multiplex
                      detection applications using the frequency mixing magnetic
                      detection (FMMD) technique. In this method, we employ a
                      low-frequency magnetic field scanning method and analyze the
                      real and imaginary parts of the measurement signal f1+
                      2⋅f2 obtained from binary mixture samples of different MNP
                      type combinations. Our findings suggest that FMMD-based
                      duplex detection can achieve effective and reliable
                      differentiation when a substantial phase response deviation
                      exists among the particles.},
      cin          = {IBI-3},
      ddc          = {620},
      cid          = {I:(DE-Juel1)IBI-3-20200312},
      pnm          = {5241 - Molecular Information Processing in Cellular Systems
                      (POF4-524)},
      pid          = {G:(DE-HGF)POF4-5241},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.1016/j.sna.2025.117095},
      url          = {https://juser.fz-juelich.de/record/1047250},
}