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| 005 | 20260122203309.0 | ||
| 024 | 7 | _ | |a 10.1111/joor.70039 |2 doi |
| 024 | 7 | _ | |a 0305-182X |2 ISSN |
| 024 | 7 | _ | |a 1365-2842 |2 ISSN |
| 024 | 7 | _ | |a 10.34734/FZJ-2026-00916 |2 datacite_doi |
| 037 | _ | _ | |a FZJ-2026-00916 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Prott, Lea S. |0 0000-0003-0792-0830 |b 0 |e Corresponding author |
| 245 | _ | _ | |a Transcutaneous Auricular Vagus Nerve Stimulation for the Treatment of Myoarthropathic Symptoms Associated With Temporomandibular Disorders—A Pilot Randomised Controlled Trial |
| 260 | _ | _ | |a Oxford [u.a.] |c 2025 |b Wiley-Blackwell |
| 336 | 7 | _ | |a article |2 DRIVER |
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| 520 | _ | _ | |a ABSTRACTBackground: Transcutaneous auricular vagus nerve stimulation (taVNS) is a safe and feasible treatment for a variety of acuteand chronic pain conditions. However, no evidence about taVNS effectiveness in patients with chronic pain associated with tem-poromandibular disorders (TMD) is available.Objective: To evaluate the feasibility of and compliance with taVNS in participants experiencing chronic TMD pain and poten-tial effects on pain, psychological well-being, muscle activity, and kinematics.Methods: Twenty adults with chronic TMD pain were randomised to receive taVNS (n = 10) or sham (n = 10). In the taVNSgroup, stimulation was performed on the left tragus for 4 h daily (25 Hz, pulse width 250 μs, 28 s on/32 s off). In the sham group,an inactive non-functional sham electrode was used. Patient-reported outcome measures (GCPS, PHQ-9, GAD-7, PHQ-15, andOHIP- G14), muscle activity, and kinematics were assessed at baseline, 4 weeks, and 8 weeks. Compliance was assessed using asmartphone app, which recorded daily stimulation time and intensity.Results: Recruitment and retention rates were high (100% and 90%, respectively), with 83% adherence to the intervention.Participants receiving taVNS showed a large effect on oral health-related quality of life, and at least a small but potentially impor-tant effect on pain intensity, anxiety, depression, severity of somatic symptoms, muscle activity, and kinematics. However, noneof these differences were statistically significant. No serious adverse events were identified. |
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| 773 | _ | _ | |a 10.1111/joor.70039 |g Vol. 52, no. 12, p. 2351 - 2360 |0 PERI:(DE-600)2007587-X |n 12 |p 2351 - 2360 |t Journal of oral rehabilitation |v 52 |y 2025 |x 0305-182X |
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