001     10735
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024 7 _ |2 pmid
|a pmid:19961958
024 7 _ |2 DOI
|a 10.1016/j.actbio.2009.11.032
024 7 _ |2 WOS
|a WOS:000278250100055
037 _ _ |a PreJuSER-10735
041 _ _ |a eng
082 _ _ |a 570
084 _ _ |2 WoS
|a Engineering, Biomedical
084 _ _ |2 WoS
|a Materials Science, Biomaterials
100 1 _ |0 P:(DE-HGF)0
|a Singh, R.
|b 0
245 _ _ |a Characterization of the deformation behavior of intermediate porosity interconnected Ti foams using micro-computed tomography and direct finite element modelling
260 _ _ |a Berlin
|b Wiley VCH
|c 2010
300 _ _ |a 2342 - 2351
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
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336 7 _ |a Journal Article
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336 7 _ |a ARTICLE
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336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |0 8163
|a Acta Biotechnologica
|v 6
|x 0138-4988
|y 6
500 _ _ |a The authors acknowledge the useful discussions and assistance of R.C. Atwood and R. Hamilton with the mu CT studies. Andreas Fritsch (Technische Universitat Wien) is gratefully acknowledged for his assistance with the continuum micromechanics modeling. We thank the European Synchrotron Radiation Facility for the provision of synchrotron radiation facilities and especially the team of beam line ID19. We would also like to thank the EPSRC (GR/T26344) for support for the computational facilities and one of the authors (R.S.) gratefully acknowledges financial support from the EC under a Marie Curie Fellowship Grant.
520 _ _ |a Under load-bearing conditions metal-based foam scaffolds are currently the preferred choice as bone/cartilage implants. In this study X-ray micro-computed tomography was used to discretize the three-dimensional structure of a commercial titanium foam used in spinal fusion devices. Direct finite element modeling, continuum micromechanics and analytical models of the foam were employed to characterize the elasto-plastic deformation behavior. These results were validated against experimental measurements, including ultrasound and monotonic and interrupted compression testing. Interrupted compression tests demonstrated localized collapse of pores unfavorably oriented with respect to the loading direction at many isolated locations, unlike the Ashby model, in which pores collapse row by row. A principal component analysis technique was developed to quantify the pore anisotropy which was then related to the yield stress anisotropy, indicating which isolated pores will collapse first. The Gibson-Ashby model was extended to incorporate this anisotropy by considering an orthorhombic, rather than a tetragonal, unit cell. It is worth noting that the natural bone is highly anisotropic and there is a need to develop and characterize anisotropic implants that mimic bone characteristics.
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|2 G:(DE-HGF)
|a Rationelle Energieumwandlung
|c P12
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Biocompatible Materials: chemistry
650 _ 2 |2 MeSH
|a Computer Simulation
650 _ 2 |2 MeSH
|a Elastic Modulus
650 _ 2 |2 MeSH
|a Finite Element Analysis
650 _ 2 |2 MeSH
|a Gases: chemistry
650 _ 2 |2 MeSH
|a Hardness
650 _ 2 |2 MeSH
|a Materials Testing
650 _ 2 |2 MeSH
|a Models, Chemical
650 _ 2 |2 MeSH
|a Stress, Mechanical
650 _ 2 |2 MeSH
|a Titanium: chemistry
650 _ 2 |2 MeSH
|a Tomography, X-Ray Computed: methods
650 _ 7 |0 0
|2 NLM Chemicals
|a Biocompatible Materials
650 _ 7 |0 0
|2 NLM Chemicals
|a Gases
650 _ 7 |0 7440-32-6
|2 NLM Chemicals
|a Titanium
650 _ 7 |2 WoSType
|a J
653 2 0 |2 Author
|a Titanium foam
653 2 0 |2 Author
|a Porous materials
653 2 0 |2 Author
|a Finite element modeling
653 2 0 |2 Author
|a X-ray micro-tomography
653 2 0 |2 Author
|a Biomaterials
700 1 _ |0 P:(DE-HGF)0
|a Lee, P.D.
|b 1
700 1 _ |0 P:(DE-HGF)0
|a Lindley, T.C.
|b 2
700 1 _ |0 P:(DE-HGF)0
|a Hellmich, C
|b 3
700 1 _ |0 P:(DE-Juel1)129591
|a Bram, M.
|b 4
|u FZJ
700 1 _ |0 P:(DE-HGF)0
|a Imwinkelried, T.
|b 5
700 1 _ |0 P:(DE-HGF)0
|a Dashwood, R.J.
|b 6
773 _ _ |0 PERI:(DE-600)2044639-1
|a 10.1016/j.actbio.2009.11.032
|g Vol. 6, p. 2342 - 2351
|p 2342 - 2351
|q 6<2342 - 2351
|t Acta biotechnologica
|v 6
|x 0138-4988
|y 2010
856 7 _ |u http://dx.doi.org/10.1016/j.actbio.2009.11.032
909 C O |o oai:juser.fz-juelich.de:10735
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