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| Hauptseite > Publikationsdatenbank > Differential activation of memory-relevant brain regions during a dialysis cycle > print |
| Hauptseite > Publikationsdatenbank > Differential activation of memory-relevant brain regions during a dialysis cycle > print |
| 001 | 10798 | ||
| 005 | 20210129210526.0 | ||
| 024 | 7 | _ | |2 pmid |a pmid:20668428 |
| 024 | 7 | _ | |2 DOI |a 10.1038/ki.2010.253 |
| 024 | 7 | _ | |2 WOS |a WOS:000282276200012 |
| 037 | _ | _ | |a PreJuSER-10798 |
| 041 | _ | _ | |a eng |
| 082 | _ | _ | |a 610 |
| 084 | _ | _ | |2 WoS |a Urology & Nephrology |
| 100 | 1 | _ | |0 P:(DE-Juel1)VDB7479 |a Lux, S. |b 0 |u FZJ |
| 245 | _ | _ | |a Differential activation of memory-relevant brain regions during a dialysis cycle |
| 260 | _ | _ | |a [S.l.] |b Wiley-Blackwell |c 2010 |
| 300 | _ | _ | |a 794 - 802 |
| 336 | 7 | _ | |0 PUB:(DE-HGF)16 |2 PUB:(DE-HGF) |a Journal Article |
| 336 | 7 | _ | |2 DataCite |a Output Types/Journal article |
| 336 | 7 | _ | |0 0 |2 EndNote |a Journal Article |
| 336 | 7 | _ | |2 BibTeX |a ARTICLE |
| 336 | 7 | _ | |2 ORCID |a JOURNAL_ARTICLE |
| 336 | 7 | _ | |2 DRIVER |a article |
| 440 | _ | 0 | |0 22941 |a Kidney International |v 78 |x 0098-6577 |
| 500 | _ | _ | |a The excellent support and cooperation of the following colleagues in dialysis centers is gratefully acknowledged: Stefan Heidenreich, Roland Bohm, Maria Ritzerfeld, KfH Aachen; Peter Weidemann, Athina Vassiliadou, Aachen; Sebastian Drube, Bernd Wolbert, Katrin Muller, Duren; Stefan Holzmann, Erkelenz; Waltraut Hofmann, Achim Fritz, KfH Linnich. In addition, the support of the following members of the MRI group of the Institute of Neurosciences and Medicine of the Research Center Julich is gratefully acknowledged: Veronika Ermer, Heiko Neeb, and Cordula Kemper. |
| 520 | _ | _ | |a Cognitive impairment is a common and largely undiagnosed finding in a significant number of dialysis patients. These alterations may result from concomitant cerebrovascular disease, hemodynamic instability, the uremic milieu, or changes induced by the dialysis process. In order to gain further insight into this, we recruited 12 stable chronic hemodialysis patients (without clinical neurological disease) and an age- and gender-matched cohort of 12 control individuals (without renal or neurological problems) in a prospective, single-center study. In order to disentangle the influence of dialysis itself on memory function, each dialysis patient was tested twice: once immediately before dialysis following a long weekend (t1) and again the day after this dialysis (t2). The control individuals were tested in the same time frame. Neuropsychological testing found that the control individuals performed significantly better in verbal learning, motor speed, task switching, verbal comprehension, word fluency, spatial visualization, spatial perception, and reasoning; all independent of the time point. Functional magnetic resonance imaging of the whole brain in seven hemodialysis patients found significantly more bilateral activation of the hippocampus during the verbal working memory task at t2 relative to t1 compared with their seven matched control counterparts. Thus, our study found differential and task-specific activation of memory-relevant brain areas during a dialysis cycle. |
| 536 | _ | _ | |0 G:(DE-Juel1)FUEK409 |2 G:(DE-HGF) |x 0 |c FUEK409 |a Funktion und Dysfunktion des Nervensystems (FUEK409) |
| 536 | _ | _ | |0 G:(DE-HGF)POF2-89572 |a 89572 - (Dys-)function and Plasticity (POF2-89572) |c POF2-89572 |f POF II T |x 1 |
| 588 | _ | _ | |a Dataset connected to Web of Science, Pubmed |
| 650 | _ | 2 | |2 MeSH |a Adult |
| 650 | _ | 2 | |2 MeSH |a Brain Mapping |
| 650 | _ | 2 | |2 MeSH |a Case-Control Studies |
| 650 | _ | 2 | |2 MeSH |a Cognition Disorders: etiology |
| 650 | _ | 2 | |2 MeSH |a Female |
| 650 | _ | 2 | |2 MeSH |a Hippocampus: physiopathology |
| 650 | _ | 2 | |2 MeSH |a Humans |
| 650 | _ | 2 | |2 MeSH |a Magnetic Resonance Imaging |
| 650 | _ | 2 | |2 MeSH |a Male |
| 650 | _ | 2 | |2 MeSH |a Memory: physiology |
| 650 | _ | 2 | |2 MeSH |a Middle Aged |
| 650 | _ | 2 | |2 MeSH |a Neuropsychological Tests |
| 650 | _ | 2 | |2 MeSH |a Prospective Studies |
| 650 | _ | 2 | |2 MeSH |a Renal Dialysis: adverse effects |
| 650 | _ | 2 | |2 MeSH |a Verbal Learning |
| 650 | _ | 2 | |2 MeSH |a Young Adult |
| 650 | _ | 7 | |2 WoSType |a J |
| 653 | 2 | 0 | |2 Author |a dementia |
| 653 | 2 | 0 | |2 Author |a dialysis volume |
| 653 | 2 | 0 | |2 Author |a end-stage renal disease |
| 653 | 2 | 0 | |2 Author |a uremia |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB1072 |a Mirzazade, S. |b 1 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)144165 |a Kuzmanovic, B. |b 2 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB90105 |a Plewan, T. |b 3 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)131678 |a Eickhoff, S. B. |b 4 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)131794 |a Shah, J. N. |b 5 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB93705 |a Floege, J. |b 6 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)131720 |a Fink, G. R. |b 7 |u FZJ |
| 700 | 1 | _ | |0 P:(DE-Juel1)VDB92610 |a Eitner, F. |b 8 |u FZJ |
| 773 | _ | _ | |0 PERI:(DE-600)2027941-3 |a 10.1038/ki.2010.253 |g Vol. 78, p. 794 - 802 |p 794 - 802 |q 78<794 - 802 |t Kidney international / Supplements |v 78 |x 0098-6577 |y 2010 |
| 856 | 7 | _ | |u http://dx.doi.org/10.1038/ki.2010.253 |
| 909 | C | O | |o oai:juser.fz-juelich.de:10798 |p VDB |
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