Home > Publications database > Control of Cell Adhesion and Neurite Outgrowth by Patterned Gold Nanoparticles with Tunable Attractive or Repulsive Surface Properties > print |
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024 | 7 | _ | |2 DOI |a 10.1002/smll.201200465 |
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041 | _ | _ | |a eng |
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100 | 1 | _ | |0 P:(DE-HGF)0 |a Gilles, S. |b 0 |
245 | _ | _ | |a Control of Cell Adhesion and Neurite Outgrowth by Patterned Gold Nanoparticles with Tunable Attractive or Repulsive Surface Properties |
260 | _ | _ | |a Weinheim |b Wiley-VCH Verl. |c 2012 |
300 | _ | _ | |a 3357 - 3367 |
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440 | _ | 0 | |0 16041 |a Small |v 8 |x 1613-6810 |y 21 |
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520 | _ | _ | |a Guiding of neuronal cells on surfaces is required for the investigation of fundamental aspects of neurobiology, for tissue engineering, and for numerous bioelectronic applications. A modular method to establish nanostructured chemical templates for local deposition of gold nanoparticles is presented. A process comprising nanoimprint lithography, silanization, lift-off, and gold nanoparticle immobilization is used to fabricate the particle patterns. The chemical composition of the surface can be modified by in situ adsorption of cell-binding ligands to locally addressed particles. The versatility of this approach is demonstrated by inverting the binding affinity between rat cortical neurons and nanopatterned surfaces via wet-chemical means and thereby reversing the pattern of guided neurons. |
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700 | 1 | _ | |0 P:(DE-Juel1)VDB71557 |a Meffert, S. |b 3 |u FZJ |
700 | 1 | _ | |0 P:(DE-Juel1)VDB109679 |a Li, P. |b 4 |u FZJ |
700 | 1 | _ | |0 P:(DE-Juel1)145556 |a Greben, K. |b 5 |u FZJ |
700 | 1 | _ | |0 P:(DE-HGF)0 |a Simon, U. |b 6 |
700 | 1 | _ | |0 P:(DE-Juel1)128713 |a Offenhäusser, A. |b 7 |u FZJ |
700 | 1 | _ | |0 P:(DE-Juel1)128707 |a Mayer, D. |b 8 |u FZJ |
773 | _ | _ | |0 PERI:(DE-600)2168935-0 |a 10.1002/smll.201200465 |g Vol. 8, p. 3357 - 3367 |p 3357 - 3367 |q 8<3357 - 3367 |t Small |v 8 |x 1613-6810 |y 2012 |
856 | 7 | _ | |u http://dx.doi.org/10.1002/smll.201200465 |
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914 | 1 | _ | |y 2012 |
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