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@ARTICLE{Feldmeyer:112040,
author = {Feldmeyer, D.},
title = {{E}xcitatory neuronal connectivity in the barrel cortex},
journal = {Frontiers in neuroanatomy},
number = {24},
issn = {1662-5129},
address = {Lausanne},
publisher = {Frontiers Research Foundation},
reportid = {PreJuSER-112040},
pages = {1 - 22},
year = {2012},
note = {I would like to thank Dr. Ted Abel for reading a previous
version of the manuscript. Furthermore, I would also like to
thank Dr. Gabriele Radnikow for many helpful suggestions and
careful reading of the final version of this manuscript.
This work was supported by the Helmholtz Foundation and
project grants form the Helmholtz Alliance on Systems
Biology and DFG Research Group "Barrel Cortex Function."},
abstract = {Neocortical areas are believed to be organized into
vertical modules, the cortical columns, and the horizontal
layers 1-6. In the somatosensory barrel cortex these columns
are defined by the readily discernible barrel structure in
layer 4. Information processing in the neocortex occurs
along vertical and horizontal axes, thereby linking
individual barrel-related columns via axons running through
the different cortical layers of the barrel cortex.
Long-range signaling occurs within the neocortical layers
but also through axons projecting through the white matter
to other neocortical areas and subcortical brain regions.
Because of the ease of identification of barrel-related
columns, the rodent barrel cortex has become a prototypical
system to study the interactions between different neuronal
connections within a sensory cortical area and between this
area and other cortical as well subcortical regions. Such
interactions will be discussed specifically for the
feed-forward and feedback loops between the somatosensory
and the somatomotor cortices as well as the different
thalamic nuclei. In addition, recent advances concerning the
morphological characteristics of excitatory neurons and
their impact on the synaptic connectivity patterns and
signaling properties of neuronal microcircuits in the
whisker-related somatosensory cortex will be reviewed. In
this context, their relationship between the structural
properties of barrel-related columns and their function as a
module in vertical synaptic signaling in the whisker-related
cortical areas will be discussed.},
keywords = {J (WoSType)},
cin = {INM-2},
ddc = {610},
cid = {I:(DE-Juel1)INM-2-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89571 - Connectivity and Activity (POF2-89571)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:22798946},
pmc = {pmc:PMC3394394},
UT = {WOS:000306291500002},
doi = {10.3389/fnana.2012.00024},
url = {https://juser.fz-juelich.de/record/112040},
}