Home > Publications database > Cognitive levels of performance account for hemispheric lateralisation effects in dyslexic and normally reading children > print

001     11234
005     20210129210539.0
024 7 _ |2 pmid
|a pmid:20633659
024 7 _ |2 DOI
|a 10.1016/j.neuroimage.2010.07.009
024 7 _ |2 WOS
|a WOS:000282165800019
037 _ _ |a PreJuSER-11234
041 _ _ |a eng
082 _ _ |a 610
084 _ _ |2 WoS
|a Neurosciences
084 _ _ |2 WoS
|a Neuroimaging
084 _ _ |2 WoS
|a Radiology, Nuclear Medicine & Medical Imaging
100 1 _ |0 P:(DE-Juel1)VDB33807
|a Heim, S.
|b 0
|u FZJ
245 _ _ |a Cognitive levels of performance account for hemispheric lateralisation effects in dyslexic and normally reading children
260 _ _ |a Orlando, Fla.
|b Academic Press
|c 2010
300 _ _ |a 1346 - 1358
336 7 _ |0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
|a Journal Article
336 7 _ |2 DataCite
|a Output Types/Journal article
336 7 _ |0 0
|2 EndNote
|a Journal Article
336 7 _ |2 BibTeX
|a ARTICLE
336 7 _ |2 ORCID
|a JOURNAL_ARTICLE
336 7 _ |2 DRIVER
|a article
440 _ 0 |0 4545
|a NeuroImage
|v 53
|x 1053-8119
|y 4
500 _ _ |a This research was supported by the German Federal Ministry of Education and Research (BMBF 01GJ0613 to S.H. and BMBF 01GJ0614 to M.G.), the National Institute of Biomedical Imaging and Bioengineering, the National Institute of Neurological Disorders and Stroke, and the National Institute of Mental Health (K.A.).
520 _ _ |a Recent theories of developmental dyslexia explain reading deficits in terms of deficient phonological awareness, attention, visual and auditory processing, or automaticity. Since dyslexia has a neurobiological basis, the question arises how the reader's proficiency in these cognitive variables affects the brain regions involved in visual word recognition. This question was addressed in two fMRI experiments with 19 normally reading children (Experiment 1) and 19 children with dyslexia (Experiment 2). First, reading-specific brain activation was assessed by contrasting the BOLD signal for reading aloud words vs. overtly naming pictures of real objects. Next, ANCOVAs with brain activation during reading the individuals' scores for all five cognitive variables assessed outside the scanner as covariates were performed. Whereas the normal readers' brain activation during reading showed co-variation effects predominantly in the right hemisphere, the reverse pattern was observed for the dyslexics. In particular, middle frontal gyrus, inferior parietal cortex, and precuneus showed contralateral effects for controls as compared to dyslexics. In line with earlier findings in the literature, these data hint at a global change in hemispheric asymmetry during cognitive processing in dyslexic readers, which, in turn, might affect reading proficiency.
536 _ _ |0 G:(DE-Juel1)FUEK409
|2 G:(DE-HGF)
|x 0
|c FUEK409
|a Funktion und Dysfunktion des Nervensystems (FUEK409)
536 _ _ |0 G:(DE-HGF)POF2-89572
|a 89572 - (Dys-)function and Plasticity (POF2-89572)
|c POF2-89572
|f POF II T
|x 1
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Brain: physiology
650 _ 2 |2 MeSH
|a Brain Mapping
650 _ 2 |2 MeSH
|a Child
650 _ 2 |2 MeSH
|a Cognition: physiology
650 _ 2 |2 MeSH
|a Dyslexia: physiopathology
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Functional Laterality: physiology
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Magnetic Resonance Imaging
650 _ 2 |2 MeSH
|a Male
650 _ 2 |2 MeSH
|a Reading
650 _ 7 |2 WoSType
|a J
700 1 _ |0 P:(DE-HGF)0
|a Grande, M.
|b 1
700 1 _ |0 P:(DE-Juel1)VDB93695
|a Meffert, E.
|b 2
|u FZJ
700 1 _ |0 P:(DE-Juel1)131678
|a Eickhoff, S. B.
|b 3
|u FZJ
700 1 _ |0 P:(DE-Juel1)VDB84395
|a Schreiber, H.
|b 4
|u FZJ
700 1 _ |0 P:(DE-Juel1)131730
|a Kukolja, J.
|b 5
|u FZJ
700 1 _ |0 P:(DE-Juel1)131794
|a Shah, J. N.
|b 6
|u FZJ
700 1 _ |0 P:(DE-HGF)0
|a Huber, W.
|b 7
700 1 _ |0 P:(DE-Juel1)131631
|a Amunts, K.
|b 8
|u FZJ
773 _ _ |0 PERI:(DE-600)1471418-8
|a 10.1016/j.neuroimage.2010.07.009
|g Vol. 53, p. 1346 - 1358
|p 1346 - 1358
|q 53<1346 - 1358
|t NeuroImage
|v 53
|x 1053-8119
|y 2010
856 7 _ |u http://dx.doi.org/10.1016/j.neuroimage.2010.07.009
909 C O |o oai:juser.fz-juelich.de:11234
|p VDB
913 2 _ |0 G:(DE-HGF)POF3-572
|1 G:(DE-HGF)POF3-570
|2 G:(DE-HGF)POF3-500
|a DE-HGF
|b Key Technologies
|l Decoding the Human Brain
|v (Dys-)function and Plasticity
|x 0
913 1 _ |0 G:(DE-HGF)POF2-89572
|a DE-HGF
|v (Dys-)function and Plasticity
|x 1
|4 G:(DE-HGF)POF
|1 G:(DE-HGF)POF3-890
|3 G:(DE-HGF)POF3
|2 G:(DE-HGF)POF3-800
|b Programmungebundene Forschung
|l ohne Programm
914 1 _ |y 2010
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |0 I:(DE-Juel1)INM-3-20090406
|g INM
|k INM-3
|l Kognitive Neurowissenschaften
|x 0
920 1 _ |0 I:(DE-Juel1)INM-1-20090406
|g INM
|k INM-1
|l Strukturelle und funktionelle Organisation des Gehirns
|x 1
920 1 _ |0 I:(DE-Juel1)INM-2-20090406
|g INM
|k INM-2
|l Molekulare Organisation des Gehirns
|x 2
920 1 _ |0 I:(DE-82)080010_20140620
|g JARA
|k JARA-BRAIN
|l Jülich-Aachen Research Alliance - Translational Brain Medicine
|x 3
920 1 _ |0 I:(DE-Juel1)INM-4-20090406
|g INM
|k INM-4
|l Physik der Medizinischen Bildgebung
|x 4
970 _ _ |a VDB:(DE-Juel1)122171
980 _ _ |a VDB
980 _ _ |a ConvertedRecord
980 _ _ |a journal
980 _ _ |a I:(DE-Juel1)INM-3-20090406
980 _ _ |a I:(DE-Juel1)INM-1-20090406
980 _ _ |a I:(DE-Juel1)INM-2-20090406
980 _ _ |a I:(DE-82)080010_20140620
980 _ _ |a I:(DE-Juel1)INM-4-20090406
980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)INM-1-20090406
981 _ _ |a I:(DE-Juel1)INM-2-20090406
981 _ _ |a I:(DE-Juel1)INM-4-20090406
981 _ _ |a I:(DE-Juel1)VDB1046

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21