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@ARTICLE{Eickhoff:11587,
      author       = {Eickhoff, S. B. and Pomjanski, W. and Jakobs, O. and
                      Zilles, K. and Langner, R.},
      title        = {{N}eural {C}orrelates of {D}eveloping and {A}dapting
                      {B}ehavioral {B}iases in {S}peeded {C}hoice {R}eactions -
                      {A}n f{MRI} {S}tudy on {P}redictive {M}otor {C}oding {F}irst
                      published online: {O}ctober 18, 2010},
      journal      = {Cerebral cortex},
      volume       = {21},
      issn         = {1047-3211},
      address      = {Oxford},
      publisher    = {Oxford Univ. Press},
      reportid     = {PreJuSER-11587},
      pages        = {1178-1191},
      year         = {2011},
      note         = {Human Brain Project (R01-MH074457-01A1 to S. B. E.); the
                      Initiative and Networking Fund of the Helmholtz Association
                      within the Helmholtz Alliance on Systems Biology (Human
                      Brain Model to K.Z., S. B. E.), the Deutsche
                      Forschungsgemeinschaft (IRTG 1328 to S. B. E.); and the
                      Helmholtz Alliance for Mental Health in an Aging Society
                      (HelMA to K.Z.).},
      abstract     = {In reaction-time (RT) tasks with unequally probable
                      stimuli, people respond faster and more accurately in
                      high-probability trials than in low-probability trials. We
                      used functional magnetic resonance imaging to investigate
                      brain activity during the acquisition and adaptation of such
                      biases. Participants responded to arrows pointing to either
                      side with different and previously unknown probabilities
                      across blocks, which were covertly reversed in the middle of
                      some blocks. Changes in response bias were modeled using the
                      development of the selective RT bias at the beginning of a
                      block and after the reversal as parametric regressors. Both
                      fresh development and reversal of an existing response bias
                      were associated with bilateral activations in inferior
                      parietal lobule, intraparietal sulcus, and supplementary
                      motor cortex. Further activations were observed in right
                      temporoparietal junction, dorsolateral prefrontal cortex,
                      and dorsal premotor cortex. Only during initial development
                      of biases at the beginning of a block, we observed
                      additional activity in ventral premotor cortex and anterior
                      insula, whereas the basal ganglia (bilaterally) were
                      recruited when the bias was adapted to reversed
                      probabilities. Taken together, these areas constitute a
                      network that updates and applies implicit predictions to
                      create an attention and motor bias according to
                      environmental probabilities that transform into specific
                      facilitation.},
      keywords     = {Adult / Bias (Epidemiology) / Brain: physiology / Brain
                      Mapping: methods / Decision Making: physiology / Female /
                      Humans / Magnetic Resonance Imaging: methods / Male / Middle
                      Aged / Nerve Net: physiology / Neuropsychological Tests:
                      standards / Probability Learning / Reaction Time: physiology
                      / Young Adult / J (WoSType)},
      cin          = {INM-2},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-2-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
                      89571 - Connectivity and Activity (POF2-89571)},
      pid          = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
      shelfmark    = {Neurosciences},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:20956614},
      UT           = {WOS:000289578900019},
      doi          = {10.1093/cercor/bhq188},
      url          = {https://juser.fz-juelich.de/record/11587},
}