001     11587
005     20210129210546.0
024 7 _ |2 pmid
|a pmid:20956614
024 7 _ |2 DOI
|a 10.1093/cercor/bhq188
024 7 _ |2 WOS
|a WOS:000289578900019
024 7 _ |a altmetric:653357
|2 altmetric
037 _ _ |a PreJuSER-11587
041 _ _ |a eng
082 _ _ |a 610
084 _ _ |2 WoS
|a Neurosciences
100 1 _ |0 P:(DE-Juel1)131678
|a Eickhoff, S. B.
|b 0
|u FZJ
245 _ _ |a Neural Correlates of Developing and Adapting Behavioral Biases in Speeded Choice Reactions - An fMRI Study on Predictive Motor Coding First published online: October 18, 2010
260 _ _ |a Oxford
|b Oxford Univ. Press
|c 2011
300 _ _ |a 1178-1191
336 7 _ |0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
|a Journal Article
336 7 _ |2 DataCite
|a Output Types/Journal article
336 7 _ |0 0
|2 EndNote
|a Journal Article
336 7 _ |2 BibTeX
|a ARTICLE
336 7 _ |2 ORCID
|a JOURNAL_ARTICLE
336 7 _ |2 DRIVER
|a article
440 _ 0 |0 1171
|a Cerebral Cortex
|v 21
|x 1047-3211
500 _ _ |a Human Brain Project (R01-MH074457-01A1 to S. B. E.); the Initiative and Networking Fund of the Helmholtz Association within the Helmholtz Alliance on Systems Biology (Human Brain Model to K.Z., S. B. E.), the Deutsche Forschungsgemeinschaft (IRTG 1328 to S. B. E.); and the Helmholtz Alliance for Mental Health in an Aging Society (HelMA to K.Z.).
520 _ _ |a In reaction-time (RT) tasks with unequally probable stimuli, people respond faster and more accurately in high-probability trials than in low-probability trials. We used functional magnetic resonance imaging to investigate brain activity during the acquisition and adaptation of such biases. Participants responded to arrows pointing to either side with different and previously unknown probabilities across blocks, which were covertly reversed in the middle of some blocks. Changes in response bias were modeled using the development of the selective RT bias at the beginning of a block and after the reversal as parametric regressors. Both fresh development and reversal of an existing response bias were associated with bilateral activations in inferior parietal lobule, intraparietal sulcus, and supplementary motor cortex. Further activations were observed in right temporoparietal junction, dorsolateral prefrontal cortex, and dorsal premotor cortex. Only during initial development of biases at the beginning of a block, we observed additional activity in ventral premotor cortex and anterior insula, whereas the basal ganglia (bilaterally) were recruited when the bias was adapted to reversed probabilities. Taken together, these areas constitute a network that updates and applies implicit predictions to create an attention and motor bias according to environmental probabilities that transform into specific facilitation.
536 _ _ |0 G:(DE-Juel1)FUEK409
|2 G:(DE-HGF)
|x 0
|c FUEK409
|a Funktion und Dysfunktion des Nervensystems (FUEK409)
536 _ _ |0 G:(DE-HGF)POF2-89571
|a 89571 - Connectivity and Activity (POF2-89571)
|c POF2-89571
|f POF II T
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588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Adult
650 _ 2 |2 MeSH
|a Bias (Epidemiology)
650 _ 2 |2 MeSH
|a Brain: physiology
650 _ 2 |2 MeSH
|a Brain Mapping: methods
650 _ 2 |2 MeSH
|a Decision Making: physiology
650 _ 2 |2 MeSH
|a Female
650 _ 2 |2 MeSH
|a Humans
650 _ 2 |2 MeSH
|a Magnetic Resonance Imaging: methods
650 _ 2 |2 MeSH
|a Male
650 _ 2 |2 MeSH
|a Middle Aged
650 _ 2 |2 MeSH
|a Nerve Net: physiology
650 _ 2 |2 MeSH
|a Neuropsychological Tests: standards
650 _ 2 |2 MeSH
|a Probability Learning
650 _ 2 |2 MeSH
|a Reaction Time: physiology
650 _ 2 |2 MeSH
|a Young Adult
650 _ 7 |2 WoSType
|a J
653 2 0 |2 Author
|a functional imaging
653 2 0 |2 Author
|a implicit prediction
653 2 0 |2 Author
|a preparation
653 2 0 |2 Author
|a probability learning
653 2 0 |2 Author
|a response bias
700 1 _ |0 P:(DE-HGF)0
|a Pomjanski, W.
|b 1
700 1 _ |0 P:(DE-HGF)0
|a Jakobs, O.
|b 2
700 1 _ |0 P:(DE-Juel1)131714
|a Zilles, K.
|b 3
|u FZJ
700 1 _ |0 P:(DE-Juel1)131693
|a Langner, R.
|b 4
|u FZJ
773 _ _ |0 PERI:(DE-600)1483485-6
|a 10.1093/cercor/bhq188
|g Vol. 21, p. 1178-1191
|p 1178-1191
|q 21<1178-1191
|t Cerebral cortex
|v 21
|x 1047-3211
|y 2011
856 7 _ |u http://dx.doi.org/10.1093/cercor/bhq188
909 C O |o oai:juser.fz-juelich.de:11587
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914 1 _ |y 2011
915 _ _ |0 StatID:(DE-HGF)0010
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980 _ _ |a UNRESTRICTED


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