Hauptseite > Publikationsdatenbank > Enantiomers of a Nonylphenol Isomer: Absolute Configurations and Estrogenic Potencies > print

001     1237
005     20200423202349.0
024 7 _ |2 pmid
|a pmid:18553459
024 7 _ |2 DOI
|a 10.1002/chir.20556
024 7 _ |2 WOS
|a WOS:000262561200003
024 7 _ |a altmetric:13594658
|2 altmetric
037 _ _ |a PreJuSER-1237
041 _ _ |a eng
082 _ _ |a 570
084 _ _ |2 WoS
|a Chemistry, Medicinal
084 _ _ |2 WoS
|a Chemistry, Analytical
084 _ _ |2 WoS
|a Chemistry, Organic
084 _ _ |2 WoS
|a Pharmacology & Pharmacy
100 1 _ |a Zhang, H.
|b 0
|0 P:(DE-HGF)0
245 _ _ |a Enantiomers of a Nonylphenol Isomer: Absolute Configurations and Estrogenic Potencies
260 _ _ |a New York, NY [u.a.]
|b Wiley Interscience
|c 2009
300 _ _ |a 271 - 275
336 7 _ |a Journal Article
|0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
440 _ 0 |a Chirality
|x 0899-0042
|0 19963
|y 2
|v 21
500 _ _ |a Contract grant sponsor: Ministry of Innovation, Science, Research and Technology of the State of North Rhine-Westphalia
520 _ _ |a Enantiomers of 4-(1,1,2-trimethylhexyl)phenol, a chiral isomer of the endocrine disrupting chemical nonylphenol, have been resolved and isolated by preparative chiral HPLC. The absolute configurations of the enantiomers were then determined by an X-ray crystallographic study of the (-)-camphanoyl derivative of the first eluted enantiomer NP(35)E1. The first enantiomer (NP(35)E1) and the second enantiomer (NP(35)E2) eluted were found to have the S and R absolute configurations, respectively. The estrogenic potencies of the S and R enantiomers were tested by the E-screen assay. A slight difference was observed in the relative proliferative effect between the S enantiomer and R enantiomer in the E-screen assay.
536 _ _ |a Terrestrische Umwelt
|c P24
|2 G:(DE-HGF)
|0 G:(DE-Juel1)FUEK407
|x 0
588 _ _ |a Dataset connected to Web of Science, Pubmed
650 _ 2 |2 MeSH
|a Animals
650 _ 2 |2 MeSH
|a Chromatography, High Pressure Liquid
650 _ 2 |2 MeSH
|a Crystallography, X-Ray
650 _ 2 |2 MeSH
|a Ecotoxicology
650 _ 2 |2 MeSH
|a Estrogens: chemistry
650 _ 2 |2 MeSH
|a Estrogens: isolation & purification
650 _ 2 |2 MeSH
|a Estrogens: toxicity
650 _ 2 |2 MeSH
|a Phenols: chemistry
650 _ 2 |2 MeSH
|a Phenols: isolation & purification
650 _ 2 |2 MeSH
|a Phenols: toxicity
650 _ 2 |2 MeSH
|a Stereoisomerism
650 _ 7 |0 0
|2 NLM Chemicals
|a Estrogens
650 _ 7 |0 0
|2 NLM Chemicals
|a Phenols
650 _ 7 |0 25154-52-3
|2 NLM Chemicals
|a nonylphenol
650 _ 7 |a J
|2 WoSType
653 2 0 |2 Author
|a endocrine disrupting chemicals
653 2 0 |2 Author
|a X-ray crystallography
653 2 0 |2 Author
|a E-screen assay
700 1 _ |a Oppel, I.M.
|b 1
|0 P:(DE-HGF)0
700 1 _ |a Spiteller, M.
|b 2
|0 P:(DE-HGF)0
700 1 _ |a Guenther, K.
|b 3
|u FZJ
|0 P:(DE-Juel1)VDB40956
700 1 _ |a Boehmler, G.
|b 4
|0 P:(DE-HGF)0
700 1 _ |a Zuehlke, S.
|b 5
|0 P:(DE-HGF)0
773 _ _ |a 10.1002/chir.20556
|g Vol. 21, p. 271 - 275
|p 271 - 275
|q 21<271 - 275
|0 PERI:(DE-600)2001237-8
|t Chirality
|v 21
|y 2009
|x 0899-0042
856 7 _ |u http://dx.doi.org/10.1002/chir.20556
856 4 _ |u https://juser.fz-juelich.de/record/1237/files/FZJ-1237.pdf
|z Published final document.
|y Restricted
909 C O |o oai:juser.fz-juelich.de:1237
|p VDB
913 1 _ |k P24
|v Terrestrische Umwelt
|l Terrestrische Umwelt
|b Erde und Umwelt
|0 G:(DE-Juel1)FUEK407
|x 0
914 1 _ |y 2009
915 _ _ |0 StatID:(DE-HGF)0010
|a JCR/ISI refereed
920 1 _ |k ICG-3
|l Phytosphäre
|d 31.10.2010
|g ICG
|0 I:(DE-Juel1)ICG-3-20090406
|x 1
970 _ _ |a VDB:(DE-Juel1)102220
980 _ _ |a VDB
980 _ _ |a ConvertedRecord
980 _ _ |a journal
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980 _ _ |a UNRESTRICTED
981 _ _ |a I:(DE-Juel1)IBG-2-20101118
981 _ _ |a I:(DE-Juel1)ICG-3-20090406

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Marc 21