TY - JOUR
AU - Müller-Schiffmann, A.
AU - März-Berberich, J.
AU - Andrjevna, A.
AU - Rönicke, R.
AU - Bartnik, D.
AU - Brener, O.
AU - Kutzsche, J.
AU - Horn, A.H.C.
AU - Hellmert, M.
AU - Gottmann, K
AU - Reymann, K.
AU - Funke, S. A.
AU - Nagel-Steger, L.
AU - Moriscot, C.
AU - Schoehn, G.
AU - Sticht, H.
AU - Willbold, D.
AU - Schrader, T.
AU - Korth, C.
TI - Combining independent drug classes into superior, synergistically acting hybrid molecules
JO - Angewandte Chemie / International edition
VL - 49
SN - 0044-8249
CY - Weinheim
PB - Wiley-VCH
M1 - PreJuSER-12405
SP - 8743 - 8746
PY - 2010
N1 - The major support for this work was from a grant of the Volkswagen-Stiftung to C. K., T. S., D. W., and H. S. (I/82 649); further funding was provided by EU-FP6 (cNEUPRO), EU-FP7 (PRIORITY) grants to C. K. and a DFG-GRK1033 grant to J.K. and C. K.
KW - Amino Acid Sequence
KW - Amyloid beta-Peptides: chemistry
KW - Animals
KW - CHO Cells
KW - Cricetinae
KW - Cricetulus
KW - Drug Design
KW - Humans
KW - Immunoprecipitation
KW - Oligopeptides: chemistry
KW - Oligopeptides: pharmacology
KW - Protein Structure, Secondary
KW - Pyrazoles: chemistry
KW - Stereoisomerism
KW - Amyloid beta-Peptides (NLM Chemicals)
KW - D3 peptide (NLM Chemicals)
KW - Oligopeptides (NLM Chemicals)
KW - Pyrazoles (NLM Chemicals)
KW - trimer-TEG-D3 (NLM Chemicals)
KW - J (WoSType)
LB - PUB:(DE-HGF)16
C6 - pmid:20922735
UR - <Go to ISI:>//WOS:000284045400042
DO - DOI:10.1002/anie.201004437
UR - https://juser.fz-juelich.de/record/12405
ER -