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@ARTICLE{Jasnin:12506,
      author       = {Jasnin, M. and Stadler, A. and Tehei, M and Zaccai, G.},
      title        = {{S}pecific cellular water dynamics observed in vivo by
                      neutron scattering and {NMR}},
      journal      = {Physical Chemistry Chemical Physics},
      volume       = {12},
      issn         = {1463-9076},
      address      = {Cambridge},
      publisher    = {RSC Publ.},
      reportid     = {PreJuSER-12506},
      pages        = {10154 - 10160},
      year         = {2010},
      note         = {Record converted from VDB: 12.11.2012},
      abstract     = {Neutron scattering, by using deuterium labelling, revealed
                      how intracellular water dynamics, measured in vivo in E.
                      coli, human red blood cells and the extreme halophile,
                      Haloarcula marismortui, depends on the cell type and nature
                      of the cytoplasm. The method uniquely permits the
                      determination of motions on the molecular length
                      (approximately ångstrøm) and time (pico- to nanosecond)
                      scales. In the bacterial and human cells, intracellular
                      water beyond the hydration shells of cytoplasmic
                      macromolecules and membrane faces flows as freely as liquid
                      water. It is not "tamed" by confinement. In contrast, in the
                      extreme halophile archaeon, in addition to free and
                      hydration water an intracellular water component was
                      observed with significantly slowed down translational
                      diffusion. The results are discussed and compared to
                      observations in E. coli and Haloarcula marismortui by
                      deuteron spin relaxation in NMR--a method that is sensitive
                      to water rotational dynamics on a wide range of time
                      scales.},
      keywords     = {Erythrocytes: metabolism / Escherichia coli: cytology /
                      Escherichia coli: metabolism / Haloarcula marismortui:
                      cytology / Haloarcula marismortui: metabolism / Hemoglobins:
                      metabolism / Humans / Magnetic Resonance Spectroscopy /
                      Neutron Diffraction / Water: metabolism / Hemoglobins (NLM
                      Chemicals) / Water (NLM Chemicals) / J (WoSType)},
      cin          = {ISB-2},
      ddc          = {540},
      cid          = {I:(DE-Juel1)ISB-2-20090406},
      pnm          = {BioSoft: Makromolekulare Systeme und biologische
                      Informationsverarbeitung},
      pid          = {G:(DE-Juel1)FUEK505},
      shelfmark    = {Chemistry, Physical / Physics, Atomic, Molecular $\&$
                      Chemical},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:20714607},
      UT           = {WOS:000281352300003},
      doi          = {10.1039/c0cp01048k},
      url          = {https://juser.fz-juelich.de/record/12506},
}