Gast ::
| Hauptseite > Workflowsammlungen > Öffentliche Einträge > Reelin Together with ApoER2 Regulates Interneuron Migration in the Olfactory Bulb > print |
| Hauptseite > Workflowsammlungen > Öffentliche Einträge > Reelin Together with ApoER2 Regulates Interneuron Migration in the Olfactory Bulb > print |
| 001 | 127931 | ||
| 005 | 20210129211046.0 | ||
| 024 | 7 | _ | |a 10.1371/journal.pone.0050646 |2 doi |
| 024 | 7 | _ | |a WOS:000312104900073 |2 WOS |
| 024 | 7 | _ | |a 2128/4888 |2 Handle |
| 037 | _ | _ | |a FZJ-2012-00877 |
| 082 | _ | _ | |a 500 |
| 100 | 1 | _ | |a Hellwig, Sabine |0 P:(DE-HGF)0 |b 0 |
| 245 | _ | _ | |a Reelin Together with ApoER2 Regulates Interneuron Migration in the Olfactory Bulb |
| 260 | _ | _ | |a Lawrence, Kan. |c 2012 |b PLoS |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 127931 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 520 | _ | _ | |a One pathway regulating the migration of neurons during development of the mammalian cortex involves the extracellular matrix protein Reelin. Reelin and components of its signaling cascade, the lipoprotein receptors ApoER2 and Vldlr and the intracellular adapter protein Dab1 are pivotal for a correct layer formation during corticogenesis. The olfactory bulb (OB) as a phylogenetically old cortical region is known to be a prominent site of Reelin expression. Although some aspects of Reelin function in the OB have been described, the influence of Reelin on OB layer formation has so far been poorly analyzed. Here we studied animals deficient for either Reelin, Vldlr, ApoER2 or Dab1 as well as double-null mutants. We performed organotypic migration assays, immunohistochemical marker analysis and BrdU incorporation studies to elucidate roles for the different components of the Reelin signaling cascade in OB neuroblast migration and layer formation. We identified ApoER2 as being the main receptor responsible for Reelin mediated detachment of neuroblasts and correct migration of early generated interneurons within the OB, a prerequisite for correct OB lamination |
| 536 | _ | _ | |a 331 - Signalling Pathways and Mechanisms in the Nervous System (POF2-331) |0 G:(DE-HGF)POF2-331 |c POF2-331 |f POF II |x 0 |
| 536 | _ | _ | |a 89571 - Connectivity and Activity (POF2-89571) |0 G:(DE-HGF)POF2-89571 |c POF2-89571 |x 1 |f POF II T |
| 588 | _ | _ | |a Dataset connected to CrossRef, juser.fz-juelich.de |
| 700 | 1 | _ | |a Hack, Iris |0 P:(DE-Juel1)141620 |b 1 |
| 700 | 1 | _ | |a Zucker, Birgit |0 P:(DE-HGF)0 |b 2 |
| 700 | 1 | _ | |a Brunne, Bianka |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Junghans, Dirk |0 P:(DE-HGF)0 |b 4 |
| 773 | _ | _ | |a 10.1371/journal.pone.0050646 |0 PERI:(DE-600)2267670-3 |n 11 |p e50646 - |t PLoS one |v 7 |y 2012 |
| 856 | 4 | _ | |y Published under CreativeCommons License |z Published final document. |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/127931/files/FZJ-127931.pdf |y OpenAccess |z Published final document. |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/127931/files/FZJ-127931.jpg?subformat=icon-1440 |x icon-1440 |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/127931/files/FZJ-127931.jpg?subformat=icon-180 |x icon-180 |y OpenAccess |
| 856 | 4 | _ | |u https://juser.fz-juelich.de/record/127931/files/FZJ-127931.jpg?subformat=icon-640 |x icon-640 |y OpenAccess |
| 909 | C | O | |o oai:juser.fz-juelich.de:127931 |p openaire |p open_access |p driver |p VDB |p dnbdelivery |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 1 |6 P:(DE-Juel1)141620 |
| 913 | 2 | _ | |a DE-HGF |b Key Technologies |l Decoding the Human Brain |1 G:(DE-HGF)POF3-570 |0 G:(DE-HGF)POF3-571 |2 G:(DE-HGF)POF3-500 |v Connectivity and Activity |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Funktion und Dysfunktion des Nervensystems |1 G:(DE-HGF)POF2-330 |0 G:(DE-HGF)POF2-331 |2 G:(DE-HGF)POF2-300 |v Signalling Pathways and Mechanisms in the Nervous System |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF2 |
| 913 | 1 | _ | |a DE-HGF |0 G:(DE-HGF)POF2-89571 |v Connectivity and Activity |x 1 |4 G:(DE-HGF)POF |1 G:(DE-HGF)POF3-890 |3 G:(DE-HGF)POF3 |2 G:(DE-HGF)POF3-800 |b Programmungebundene Forschung |l ohne Programm |
| 914 | 1 | _ | |y 2012 |
| 915 | _ | _ | |a Creative Commons Attribution CC BY 3.0 |0 LIC:(DE-HGF)CCBY3 |2 HGFVOC |
| 915 | _ | _ | |a JCR/ISI refereed |0 StatID:(DE-HGF)0010 |2 StatID |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0500 |2 StatID |b DOAJ |
| 915 | _ | _ | |a OpenAccess |0 StatID:(DE-HGF)0510 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1040 |2 StatID |b Zoological Record |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |
| 920 | 1 | _ | |0 I:(DE-Juel1)INM-2-20090406 |k INM-2 |l Molekulare Organisation des Gehirns |x 0 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a UNRESTRICTED |
| 980 | _ | _ | |a JUWEL |
| 980 | _ | _ | |a FullTexts |
| 980 | _ | _ | |a I:(DE-Juel1)INM-2-20090406 |
| 980 | _ | _ | |a VDB |
| 980 | 1 | _ | |a FullTexts |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|