guest ::
| Home > PGI-8 > A nanoporous alumina microelectrode array for functional cell–chip coupling > print |
| 001 | 128612 | ||
| 005 | 20240619091051.0 | ||
| 024 | 7 | _ | |a 10.1088/0957-4484/23/49/495303 |2 doi |
| 024 | 7 | _ | |a 1361-6528 |2 ISSN |
| 024 | 7 | _ | |a 0957-4484 |2 ISSN |
| 024 | 7 | _ | |a WOS:000311431400009 |2 WOS |
| 037 | _ | _ | |a FZJ-2013-00346 |
| 082 | _ | _ | |a 530 |
| 100 | 1 | _ | |a Wesche, Manuel |b 0 |u FZJ |
| 245 | _ | _ | |a A nanoporous alumina microelectrode array for functional cell–chip coupling |
| 260 | _ | _ | |a Bristol |c 2012 |b IOP Publ. |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1358868349_1726 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a article |2 DRIVER |
| 520 | _ | _ | |a The design of electrode interfaces has a strong impact on cell-based bioelectronic applications. We present a new type of microelectrode array chip featuring a nanoporous alumina interface. The chip is fabricated in a combination of top-down and bottom-up processes using state-of-the-art clean room technology and self-assembled generation of nanopores by aluminum anodization. The electrode characteristics are investigated in phosphate buffered saline as well as under cell culture conditions. We show that the modified microelectrodes exhibit decreased impedance compared to planar microelectrodes, which is caused by a nanostructuring effect of the underlying gold during anodization. The stability and biocompatibility of the device are demonstrated by measuring action potentials from cardiomyocyte-like cells growing on top of the chip. Cross sections of the cell–surface interface reveal that the cell membrane seals the nanoporous alumina layer without bending into the sub-50 nm apertures. The nanoporous microelectrode array device may be used as a platform for combining extracellular recording of cell activity with stimulating topographical cues. |
| 536 | _ | _ | |a 423 - Sensorics and bioinspired systems (POF2-423) |0 G:(DE-HGF)POF2-423 |c POF2-423 |x 0 |f POF II |
| 536 | _ | _ | |a 453 - Physics of the Cell (POF2-453) |0 G:(DE-HGF)POF2-453 |c POF2-453 |x 1 |f POF II |
| 588 | _ | _ | |a Dataset connected to CrossRef, juser.fz-juelich.de |
| 700 | 1 | _ | |a Hüske, Martin |0 P:(DE-Juel1)128689 |b 1 |
| 700 | 1 | _ | |a Yakushenko, Alexey |0 P:(DE-Juel1)138367 |b 2 |
| 700 | 1 | _ | |a Brüggemann, Dorothea |0 P:(DE-HGF)0 |b 3 |
| 700 | 1 | _ | |a Mayer, Dirk |0 P:(DE-Juel1)128707 |b 4 |
| 700 | 1 | _ | |a Offenhäusser, Andreas |0 P:(DE-Juel1)128713 |b 5 |
| 700 | 1 | _ | |a Wolfrum, Bernhard |0 P:(DE-Juel1)128745 |b 6 |e Corresponding author |
| 773 | _ | _ | |a 10.1088/0957-4484/23/49/495303 |g Vol. 23, no. 49, p. 495303 - |0 PERI:(DE-600)1362365-5 |n 49 |p 495303 - |t Nanotechnology |v 23 |y 2012 |x 1361-6528 |
| 856 | 4 | _ | |u http://iopscience.iop.org/0957-4484/23/49/495303 |
| 909 | C | O | |o oai:juser.fz-juelich.de:128612 |p VDB |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 0 |6 P:(DE-HGF)0 |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 1 |6 P:(DE-Juel1)128689 |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 2 |6 P:(DE-Juel1)138367 |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 4 |6 P:(DE-Juel1)128707 |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 5 |6 P:(DE-Juel1)128713 |
| 910 | 1 | _ | |a Forschungszentrum Jülich GmbH |0 I:(DE-588b)5008462-8 |k FZJ |b 6 |6 P:(DE-Juel1)128745 |
| 913 | 2 | _ | |a DE-HGF |b Key Technologies |l BioSoft Fundamentals for future Technologies in the fields of Soft Matter and Life Sciences |1 G:(DE-HGF)POF3-550 |0 G:(DE-HGF)POF3-552 |2 G:(DE-HGF)POF3-500 |v Engineering Cell Function |x 0 |
| 913 | 1 | _ | |a DE-HGF |b Schlüsseltechnologien |1 G:(DE-HGF)POF2-420 |0 G:(DE-HGF)POF2-423 |2 G:(DE-HGF)POF2-400 |v Sensorics and bioinspired systems |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF2 |l Grundlagen zukünftiger Informationstechnologien |
| 913 | 1 | _ | |a DE-HGF |b Schlüsseltechnologien |1 G:(DE-HGF)POF2-450 |0 G:(DE-HGF)POF2-453 |2 G:(DE-HGF)POF2-400 |v Physics of the Cell |x 1 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF2 |l BioSoft |
| 914 | 1 | _ | |y 2012 |
| 915 | _ | _ | |a JCR/ISI refereed |0 StatID:(DE-HGF)0010 |2 StatID |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0110 |2 StatID |b Science Citation Index |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1150 |2 StatID |b Current Contents - Physical, Chemical and Earth Sciences |
| 920 | _ | _ | |l yes |
| 920 | 1 | _ | |0 I:(DE-Juel1)PGI-8-20110106 |k PGI-8 |l Bioelektronik |x 0 |
| 920 | 1 | _ | |0 I:(DE-82)080009_20140620 |k JARA-FIT |l Jülich-Aachen Research Alliance - Fundamentals of Future Information Technology |x 1 |
| 920 | 1 | _ | |0 I:(DE-Juel1)ICS-8-20110106 |k ICS-8 |l Bioelektronik |x 2 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a I:(DE-Juel1)PGI-8-20110106 |
| 980 | _ | _ | |a I:(DE-82)080009_20140620 |
| 980 | _ | _ | |a I:(DE-Juel1)ICS-8-20110106 |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a UNRESTRICTED |
| 981 | _ | _ | |a I:(DE-Juel1)IBI-3-20200312 |
| 981 | _ | _ | |a I:(DE-Juel1)ICS-8-20110106 |
| 981 | _ | _ | |a I:(DE-Juel1)VDB881 |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|