BMBF 01EZ0822
NCFHEB NorChlor Fluor HomoEpiBatidin (NCFHEB) a potential positron emission tomography (PET) marker of early Alzheimer's disease NorChloro Fluoro HomoEpiBatidin (NCFHEB) ein potentieller Positronen Emission Tomographie (PET) Marker der frühen Alzheimer Demenz NorChloro-Fluoro HomoEpiBatidin (NCFHEB) ein potentieller Positronen-Emission Tomographie-(PET) Marker der frühen Alzheimer-Demenz
Coordinator | Osama Sabri |
Grant period | 2008-07-01 - 2012-06-30 |
Funding body | Bundesministerium für Bildung und Forschung |
BMBF | |
Identifier | G:(DE-Juel1)BMBF-01EZ0822 |
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Abstract
Comparison of the novel α4β2 nicotinic acetylcholine receptor PET radioligands (-)-Flubatine and (+)-Flubatine in Healthy Controls
NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683635]
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Abstract
Impact of APOE ε4 genotype on α4β2 nicotinic acetylcholine receptor availability in mild Alzheimer's dementia: a (-)-F-18-Flubatine PET study
NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 2019
[10.1055/s-0039-1683487]
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Abstract
Influence of APOE genotype on alpha 4 beta 2 nicotinic acetylcholine receptor binding in mild Alzheimer‘s dementia as assessed by (-)-[18F] Flubatine PET.
Annual Congress of the European Association of Nuclear Medicine, BarcelonaBarcelona, Spain, 12 Oct 2019 - 16 Oct 2019
[10.1007/s00259-019-04486-2]
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Abstract
Cognitive correlates of α4β2 nicotinic acetylcholine receptor (α4β2-nAChR) availability in mild Alzheimer’s dementia (AD) investigated with (-)-[F-18]Flubatine PET.
Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN, BremenBremen, Germany, 18 Apr 2018 - 21 Apr 2018
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Associations between alpha 4 beta 2 nicotinic acetylcholine receptor (alpha 4 beta 2-nAChR) availability and memory, executive function and attention in mild Alzheimer’s dementia (AD): a (-)-[F-18]Flubatine PET investigation.
SNMMI, PhiladelphiaPhiladelphia, USA, 23 Jun 2018 - 26 Jun 2018
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Journal Article
Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer’s dementia
Brain 141(6), 1840 - 1854 (2018) [10.1093/brain/awy099]
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Journal Article
First-in-human PET quantification study of cerebral α4β2* nicotinic acetylcholine receptors using the novel specific radioligand (−)-[ 18 F]Flubatine
NeuroImage 118, 199 - 208 (2015) [10.1016/j.neuroimage.2015.05.065]
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Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (−)-[18F]Flubatine in humans
Nuclear medicine and biology 41(6), 489 - 494 (2014) [10.1016/j.nucmedbio.2014.03.018]
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Review/Journal Article
Viewpoints on Medical Image Processing: From Science to Application
Current medical imaging reviews 9(2), 79 - 88 (2013) [10.2174/1573405611309020002]
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Journal Article
Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application.
Applied radiation and isotopes 80, 7-11 (2013) [10.1016/j.apradiso.2013.05.009]
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All known publications ...
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