Record #131848

NikotinPET

Validierung von (+)-[18F]Flubatine als PET-Radiotracer zur Untersuchung von Nikotinrezeptoren bei Demenz

Coordinator	Peter Brust
Grant period	2012-09-01 - 2015-02-28
Funding body	Helmholtz Gemeinschaft Deutscher Forschungszentren
Identifier	G:(DE-Juel1)HGF-HVF-0012

Recent Publications

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Journal Article Tiepolt, S. (Corresponding author) ; Becker, G.-A. ; Wilke, S. ; Cecchin, D. ; Rullmann, M. ; Meyer, P. M. ; Barthel, H. ; Hesse, S. ; Patt, M. ; Luthardt, J. ; Wagenknecht, G.FZJ* ; Sattler, B. ; Deuther-Conrad, W. ; Ludwig, F.-A. ; Fischer, S. ; Gertz, H.-J. ; Smits, R. ; Hoepping, A. ; Steinbach, J. ; Brust, P. ; Sabri, O.
(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls
European journal of nuclear medicine and molecular imaging 48(3), 731 - 746 (2021) [10.1007/s00259-020-05029-w]2021 Files Fulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

Abstract Wilke, S. (Corresponding author) ; Tiepolt, S. ; Rullmann, M. ; Meyer, P. M. ; Hesse, S. ; Patt, M. ; Luthardt, J. ; Barthel, H. ; Wagenknecht, G.FZJ* ; Smits, R. ; Hoepping, A. ; Sattler, B. ; Deuther-Conrad, W. ; Gertz, H. J. ; Brust, P. ; Becker, G. A. ; Sabri, O.
Comparison of the novel α4β2 nicotinic acetylcholine receptor PET radioligands (-)-Flubatine and (+)-Flubatine in Healthy Controls
2019NuklearMedizin 2019, BremenBremen, Germany, 3 Apr 2019 - 6 Apr 20192019-04-032019-04-06 [10.1055/s-0039-1683635] BibTeX | EndNote: XML, Text | RIS

Abstract Tiepolt, S. (Corresponding author) ; Becker, G. A. ; Wilke, S. ; Cecchin, D. ; Meyer, P. M. ; Barthel, H. ; Hesse, S. ; Patt, M. ; Rullmann, M. ; Wagenknecht, G.FZJ* ; Deuther-Conrad, W. ; Ludwig, F. A. ; Wagner, A. ; Gertz, H. J. ; Smits, R. ; Hoepping, A. ; Steinbach, J. ; Brust, P. ; Sabri, O.
(+)-[18F]Flubatine ein neuer α4β2* nikotinischer Acetylcholin-Rezeptor (nAChR) PET Radioligand – Ergebnisse der First-In-Human Studie bei Patienten mit Alzheimer Demenz (AD) und gesunden Probanden (HC).
2018Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin, DGN, BremenBremen, Germany, 18 Apr 2018 - 21 Apr 20182018-04-182018-04-21 BibTeX | EndNote: XML, Text | RIS

Abstract Becker, G. A. (Corresponding author) ; Tiepolt, S. ; Patt, M. ; Luthardt, J. ; Rullmann, M. ; Hesse, S. ; Wilke, S. ; Meyer, P. M. ; Barthel, H. ; Wagenknecht, G.FZJ* ; Höpping, A. ; Gertz, H. J. ; Steinbach, J. ; Brust, P. ; Sabri, O.
Kinetic Modeling of (+)-[18F]Flubatine Binding to Nicotinic α4β2* Acetylcholine Receptors in Human Brains
2016Neuroreceptor Mapping Conference, NRM, BostonBoston, USA, 13 Jul 2016 - 16 Jul 20162016-07-132016-07-16 BibTeX | EndNote: XML, Text | RIS

Contribution to a conference proceedings/Contribution to a book Schwieger, R. (Corresponding author)FZJ* ; Wagenknecht, G. (Thesis advisor)FZJ*
Surface Reconstruction of Medical 3D Data
2014Aachener Schriften zur Medizinischen Informatik, V9(2)
Hauptseminar im Wintersemester 2013/14 Medizinische Bildverarbeitung, AachenAachen, Germany, Aachen : Universitätsklinikum Aachen, Aachener Schriften zur Medizinischen Informatik V 9, B 2 182 S : Ill., graph. Darst (2014)2014 BibTeX | EndNote: XML, Text | RIS

Review/Journal Article Deserno, T. M. (Corresponding author) ; Handels, H. ; Maier-Hein, K. H. ; Mersmann, S. ; Palm, C. ; Tolxdorff, T. ; Wagenknecht, G.ZEA-2* ; Wittenberg, T.
Viewpoints on Medical Image Processing: From Science to Application
Current medical imaging reviews 9(2), 79 - 88 (2013) [10.2174/1573405611309020002]2013 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Patt, M. (Corresponding author) ; Schildan, A. ; B, H. ; Fischer, S. ; Hiller, A. ; Deuther-Conrad, W. ; Wilke, S. ; Smits, R. ; Hoepping, A. ; Wagenknecht, G.ZEA-2*FZJ* ; J, S. ; Brust, P. ; Sabri, O.
Fully automated radiosynthesis of both enantiomers of [18F]Flubatine under GMP conditions for human application.
Applied radiation and isotopes 80, 7-11 (2013) [10.1016/j.apradiso.2013.05.009]2013 Files BibTeX | EndNote: XML, Text | RIS

Poster (Other) Becker, G. (. a. (Corresponding author) ; Wilke, S. ; Schönknecht, P. ; Patt, M. ; Luthardt, J. ; Hesse, S. ; Meyer, P. ; Barthel, H. ; Sorger, D. ; Seese, A. ; Wagenknecht, G.ZEA-2*FZJ* ; Höpping, A. ; Fischer, S. ; Brust, P. ; Sabri, O.
Comparison of (-)-[18F]-Flubatine and 2-[18F]FA-85380 Binding to Nicotinic alpha4beta2 Acetylcholine Receptors in Human Brains.
2013Annual Congress of the European Association of Nuclear Medicine, EANM 2013, LyonLyon, France, 19 Oct 2013 - 23 Oct 20132013-10-192013-10-23 BibTeX | EndNote: XML, Text | RIS

Journal Article Becker, G. (Corresponding author) ; Wilke, S. ; Schönknecht, P. ; Patt, M. ; Luthardt, J. ; Hesse, S. ; Meyer, P. ; Barthel, H. ; Sorger, D. ; Seese, A. ; Wagenknecht, G.ZEA-2*FZJ* ; Höpping, A. ; Fischer, S. ; Brust, P. ; Sabri, O.
Comparison of (-)-[18F]-Flubatine and 2-[18F]FA-85380 Binding to Nicotinic alpha4beta2 Acetylcholine Receptors in Human Brains.
European journal of nuclear medicine and molecular imaging 40 (Suppl 2), S271 (2013)2013 BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Other) Pilz, T. (Corresponding author)ZEA-2*FZJ* ; Fried, E.ZEA-2*FZJ* ; van Waasen, S.ZEA-2*FZJ* ; Wagenknecht, G.ZEA-2*FZJ*
Improvement of an Active Surface Model by Adaptive External Forces
2013Bildverarbeitung für die Medizin 2013, BVM 2013, HeidelbergHeidelberg, Germany, 3 Mar 2013 - 5 Mar 20132013-03-032013-03-05 BibTeX | EndNote: XML, Text | RIS

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Record created 2013-01-28, last modified 2013-01-28

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