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@ARTICLE{Halsband:136191,
author = {Halsband, U. and Krause, B. J. and Schmidt, D. and Herzog,
H. and Tellmann, L. and Müller-Gärtner, H. -W.},
title = {{E}ncoding and retrieval in declarative learning: a
positron emission tomography study},
journal = {Behavioural brain research},
volume = {97},
publisher = {Elsevier},
reportid = {PreJuSER-136191},
pages = {69–78},
note = {Record converted from JUWEL: 18.07.2013},
abstract = {We present neuroanatomical correlates of encoding and
retrieval in an episodic memory task using visually
presented highly imaginable word-pair associates. A total of
13 right-handed normal male volunteers took part in the
study. Each subject underwent six 15O-butanol PET scans. On
each of the six trials the memory task began 30 s before the
injection of a bolus of 15O-butanol. The subjects had to
learn and retrieve 12 word pairs (highly imaginable words,
not semantically related, hard associations). The
presentation of nonsense words served as a reference
condition. Recall accuracy after 2–4 presentations was
$66.1\%921.1$ correct during the PET measurement so that
scanning during the retrieval of word pair associates was
appropriate to capture the brain activity associated with
retrieval. The results obtained support the hypothesis of
the presence of an asymmetric network consisting of
distributed brain structures subserving associative memory.
We show left dorsolateral prefrontal activation during the
encoding of visually presented word pair associates, whereas
retrieval led to bilateral frontal activation. Furthermore,
the importance of the precuneus in the retrieval of highly
imaginable word-pair associates using visual imagery as a
mnemonic strategy is demonstrated.},
keywords = {Episodic memory / Positron emission tomography / Prefrontal
/ Cortex / Precuneus / Associative learning},
cin = {INM-4},
ddc = {500},
cid = {I:(DE-Juel1)INM-4-20090406},
typ = {PUB:(DE-HGF)16},
url = {https://juser.fz-juelich.de/record/136191},
}