001     136205
005     20200423205003.0
024 7 _ |2 doi
|a 10.1007/s002210050853
024 7 _ |2 Handle
|a 2128/3755
024 7 _ |a WOS:000082947200007
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037 _ _ |a PreJuSER-136205
041 _ _ |a English
082 _ _ |a 500
100 1 _ |a Mottaghy, F. M.
|b 0
245 _ _ |a Neuronal correlates of encoding and retrieval in episodic memory during a paired-word association learning task: a functional magnetic resonance imaging study
260 _ _ |b Springer
336 7 _ |0 PUB:(DE-HGF)16
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500 _ _ |a Record converted from JUWEL: 18.07.2013
500 _ _ |a The final publication is available at http://www.springerlink.com/content/a08981g3dhml7x89/?p=29473c810da7443e9b4dc39e8b32bc81&pi=6
520 _ _ |a The investigation of memory function using functional magnetic resonance imaging (fMRI) is an expanding field of research. The aim of this study was to demonstrate brain-activity patterns related to a word-pair association task employing a whole-brain EPI sequence. Six right-handed, healthy male volunteers (mean age: 27.5 years) took part in the study. fMRI was performed at a field strength of 1.5 Tesla with 26–32 slices parallel to the AC-PC line, depending on individual brain size. Distributed brain regions were activated in episodic encoding and retrieval with similarities, but also (distinct) differences in activation patterns. Bilateral prefrontal cortical areas were involved when comparing encoding as well as retrieval to the reference condition (nonsense words). Furthermore, activation was observed in cerebellar areas during encoding, and activation in bilateral parietal areas (precuneus and inferior parietal cortex) was differentially more pronounced during retrieval. The activation of left dorsomedial thalamus during retrieval of high imagery-content word-pair associates may point to the role of this structure in episodic retrieval. The direct cognitive subtraction of encoding minus retrieval yielded a differentially larger left prefrontal activation. There was a differentially higher right prefrontal activation during retrieval than during encoding, underlining the proposed right/left asymmetry for episodic memory processes.
650 _ 7 |a Episodic memory
650 _ 7 |a Paired word association
650 _ 7 |a fMRI
700 1 _ |0 P:(DE-Juel1)131794
|a Shah, N. J.
|b 1
700 1 _ |0 P:(DE-Juel1)VDB834
|a Krause, B. J.
|b 2
700 1 _ |a Schmidt, D.
|b 3
700 1 _ |0 P:(DE-Juel1)VDB3937
|a Halsband, U.
|b 4
700 1 _ |a Jäncke, L.
|b 5
700 1 _ |a Müller-Gärtner, H. -W.
|b 6
773 _ _ |0 PERI:(DE-600)1459099-2
|a 10.1007/s002210050853
|i 3
|p 332 - 342
|t Experimental brain research
|v 128
|x 0014-4819
|y 1999
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