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@ARTICLE{Stephan:136208,
      author       = {Stephan, K. M. and Binkofski, F. and Halsband, U. and
                      Dohle, C. and Wunderlich, G. and Schnitzler, A. and Tass, P.
                      and Posse, S. and Herzog, H. and Sturm, V. and Zilles, K.
                      and Seitz, R. J. and Freund, H. -J.},
      title        = {{T}he role of ventral medial wall motor areas in bimanual
                      co-ordination. {A} combined lesion and activation study},
      journal      = {Brain},
      volume       = {122},
      issn         = {0006-8950},
      publisher    = {Oxford University Press},
      reportid     = {PreJuSER-136208},
      pages        = {351-368},
      note         = {Record converted from JUWEL: 18.07.2013},
      abstract     = {Two patients with midline tumours and disturbances of
                      bimanual co-ordination as the presenting symptoms were
                      examined. Both reported difficulties whenever the two hands
                      had to act together simultaneously, whereas they had no
                      problems with unimanual dexterity or the use of both hands
                      sequentially. In the first patient the lesion was confined
                      to the cingulate gyrus; in the second it also invaded the
                      corpus callosum and the supplementary motor area. Kinematic
                      analysis of bimanual in-phase and anti-phase movements
                      revealed an impairment of both the temporal adjustment
                      between the hands and the independence of movements between
                      the two hands. A functional imaging study in six volunteers,
                      who performed the same bimanual in-phase and anti-phase
                      tasks, showed strong activations of midline areas including
                      the cingulate and ventral supplementary motor area. The
                      prominent activation of the ventral medial wall motor areas
                      in the volunteers in conjunction with the bimanual
                      co-ordination disorder in the two patients with lesions
                      compromising their function is evidence for their pivotal
                      role in bimanual co-ordination.},
      keywords     = {medial wall motor areas / cingulate motor areas /
                      supplementary motor area / neuroimaging},
      cin          = {INM-4},
      ddc          = {500},
      cid          = {I:(DE-Juel1)INM-4-20090406},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000078756900017},
      doi          = {10.1093/brain/122.2.351},
      url          = {https://juser.fz-juelich.de/record/136208},
}