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005     20231113125538.0
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|a 10.1093/brain/122.2.351
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|a Stephan, K. M.
|b 0
245 _ _ |a The role of ventral medial wall motor areas in bimanual co-ordination. A combined lesion and activation study
260 _ _ |b Oxford University Press
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500 _ _ |a Record converted from JUWEL: 18.07.2013
520 _ _ |a Two patients with midline tumours and disturbances of bimanual co-ordination as the presenting symptoms were examined. Both reported difficulties whenever the two hands had to act together simultaneously, whereas they had no problems with unimanual dexterity or the use of both hands sequentially. In the first patient the lesion was confined to the cingulate gyrus; in the second it also invaded the corpus callosum and the supplementary motor area. Kinematic analysis of bimanual in-phase and anti-phase movements revealed an impairment of both the temporal adjustment between the hands and the independence of movements between the two hands. A functional imaging study in six volunteers, who performed the same bimanual in-phase and anti-phase tasks, showed strong activations of midline areas including the cingulate and ventral supplementary motor area. The prominent activation of the ventral medial wall motor areas in the volunteers in conjunction with the bimanual co-ordination disorder in the two patients with lesions compromising their function is evidence for their pivotal role in bimanual co-ordination.
542 _ _ |l Copyright: Oxford University Press This is an electronic version of an article published in Brain (1999) 122, 351-368. The final publication is available at http://brain.oxfordjournals.org/content/vol122/issue2/index.dtl
650 _ 7 |a medial wall motor areas
650 _ 7 |a cingulate motor areas
650 _ 7 |a supplementary motor area
650 _ 7 |a neuroimaging
700 1 _ |a Binkofski, F.
|b 1
700 1 _ |0 P:(DE-Juel1)VDB3937
|a Halsband, U.
|b 2
700 1 _ |a Dohle, C.
|b 3
700 1 _ |0 P:(DE-Juel1)VDB1817
|a Wunderlich, G.
|b 4
700 1 _ |a Schnitzler, A.
|b 5
700 1 _ |0 P:(DE-Juel1)131884
|a Tass, P.
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700 1 _ |0 P:(DE-Juel1)VDB1280
|a Posse, S.
|b 7
700 1 _ |a Herzog, H.
|b 8
700 1 _ |0 P:(DE-Juel1)VDB1606
|a Sturm, V.
|b 9
700 1 _ |0 P:(DE-Juel1)131714
|a Zilles, K.
|b 10
700 1 _ |0 P:(DE-Juel1)VDB1506
|a Seitz, R. J.
|b 11
700 1 _ |a Freund, H. -J.
|b 12
773 _ _ |0 PERI:(DE-600)1474117-9
|a 10.1093/brain/122.2.351
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|p 351-368
|t Brain
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|y 1999
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