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005     20210129212129.0
020 _ _ |a 978-3-642-10768-9
024 7 _ |a altmetric:20556101
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037 _ _ |a FZJ-2013-04204
100 1 _ |a Egger, V.
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|e Corresponding author
245 _ _ |a Electrical Activity in Neurons
260 _ _ |a Berlin Heidelberg
|c 2013
|b Springer-Verlag
295 1 0 |a Neurosciences - From Molecule to Behavior: a university textbook
300 _ _ |a 113-143
336 7 _ |a Contribution to a book
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336 7 _ |a bookPart
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336 7 _ |a BOOK_CHAPTER
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336 7 _ |a Book Section
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336 7 _ |a INBOOK
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336 7 _ |a Output Types/Book chapter
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500 _ _ |3 POF3_Assignment on 2016-02-29
520 _ _ |a To exchange and process information cells rely mostly on biochemical signalling pathways. Since these pathways are not well suited to rapidly transmit signals over larger distances, neurons use electrical activity in addition, exploiting the energy stored in the electrical gradients across cellular membranes. These gradients result from the uneven distribution of ions between the intra- and extracellular space due to the ongoing activity of ion transporters and pumps and the fact that the membrane is semipermeable for certain ions. The resulting membrane potential allows for fast flow of ions across cellular membranes via specialized classes of membrane-spanning proteins, namely ion channels. In neurons, some of these channels are voltage-gated, creating an electrical feedback loop that can generate stereotyped, regenerative depolarizing responses. Voltage-gated channels mediate the generation and conduction of action potentials and the release of transmitters at the synapse.
536 _ _ |a 331 - Signalling Pathways and Mechanisms in the Nervous System (POF2-331)
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700 1 _ |a Feldmeyer, Dirk
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856 4 _ |u http://link.springer.com/book/10.1007/978-3-642-10769-6/page/1
909 _ _ |p VDB
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910 1 _ |a Forschungszentrum Jülich GmbH
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913 2 _ |a DE-HGF
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|l Decoding the Human Brain
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|v Addenda
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913 1 _ |a DE-HGF
|b Gesundheit
|l Funktion und Dysfunktion des Nervensystems
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|v Signalling Pathways and Mechanisms in the Nervous System
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914 1 _ |y 2013
920 1 _ |0 I:(DE-Juel1)INM-2-20090406
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980 _ _ |a contb
980 _ _ |a VDB
980 _ _ |a UNRESTRICTED
980 _ _ |a I:(DE-Juel1)INM-2-20090406


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