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@ARTICLE{Hitzbleck:138442,
      author       = {Hitzbleck, Martina and Vu, Xuan Thang and Ingebrandt, Sven
                      and Offenhäusser, Andreas and Mayer, Dirk},
      title        = {{F}unctional peptides for capacitative detection of {C}a 2+
                      ions54},
      journal      = {Physica status solidi / A},
      volume       = {210},
      number       = {5},
      issn         = {1862-6300},
      address      = {Weinheim},
      publisher    = {Wiley-VCH},
      reportid     = {FZJ-2013-04573},
      pages        = {1030 - 1037},
      year         = {2013},
      abstract     = {Molecular recognition is the key feature of bioinspired
                      sensor applications. A profound understanding of recognitive
                      binding events is crucial for the design of highly specific
                      and effective binding molecules. In this paper a series of
                      simple to complex oligopeptides, derived from the Ca2+
                      chelator ethylenediaminetetraacetic acid (EDTA) and the Ca2+
                      binding protein calmodulin, were investigated. It was shown,
                      that specifically designed oligopeptides can fulfil
                      protein-like recognition functions but are much easier to
                      immobilize and enable high functional integration. Impedance
                      spectroscopy (IS) could be used to detect binding of Ca2+ to
                      different peptides because the double layer capacitance is
                      highly sensitive to changes in the morphology and dielectric
                      properties of adsorbate layers. Finally, the designed
                      functional oligopeptides were implemented in silicon
                      nanowire field effect transistors (SiNW FETs) as a proof of
                      concept for future problem-optimized molecules in sensor
                      devices.},
      cin          = {ICS-8 / PGI-8 / JARA-FIT},
      ddc          = {530},
      cid          = {I:(DE-Juel1)ICS-8-20110106 / I:(DE-Juel1)PGI-8-20110106 /
                      $I:(DE-82)080009_20140620$},
      pnm          = {423 - Sensorics and bioinspired systems (POF2-423) / 453 -
                      Physics of the Cell (POF2-453)},
      pid          = {G:(DE-HGF)POF2-423 / G:(DE-HGF)POF2-453},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000319151900033},
      doi          = {10.1002/pssa.201200886},
      url          = {https://juser.fz-juelich.de/record/138442},
}