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@ARTICLE{Maybeck:139343,
author = {Maybeck, Vanessa and Edgington, Robert and Bongrain,
Alexandre and Welch, Joseph O. and Scorsone, Emanuel and
Bergonzo, Philippe and Jackman, Richard B. and
Offenhäusser, Andreas},
title = {{B}oron-{D}oped {N}anocrystalline {D}iamond
{M}icroelectrode {A}rrays {M}onitor {C}ardiac {A}ction
{P}otentials},
journal = {Advanced Healthcare Materials},
volume = {3},
number = {2},
issn = {2192-2640},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {FZJ-2013-05340},
pages = {283–289},
year = {2014},
abstract = {The expansion of diamond-based electronics in the area of
biological interfacing has not been as thoroughly explored
as applications in electrochemical sensing. However, the
biocompatibility of diamond, large safe electrochemical
window, stability, and tunable electronic properties provide
opportunities to develop new devices for interfacing with
electrogenic cells. Here, the fabrication of microelectrode
arrays (MEAs) with boron-doped nanocrystalline diamond
(BNCD) electrodes and their interfacing with
cardiomyocyte-like HL-1 cells to detect cardiac action
potentials are presented. A nonreductive means of
structuring doped and undoped diamond on the same substrate
is shown. The resulting BNCD electrodes show high stability
under mechanical stress generated by the cells. It is shown
that by fabricating the entire surface of the MEA with NCD,
in patterns of conductive doped, and isolating undoped
regions, signal detection may be improved up to four-fold
over BNCD electrodes passivated with traditional isolators.},
cin = {ICS-8 / PGI-8 / JARA-FIT},
ddc = {540},
cid = {I:(DE-Juel1)ICS-8-20110106 / I:(DE-Juel1)PGI-8-20110106 /
I:(DE-Juel1)VDB881},
pnm = {423 - Sensorics and bioinspired systems (POF2-423) / 453 -
Physics of the Cell (POF2-453)},
pid = {G:(DE-HGF)POF2-423 / G:(DE-HGF)POF2-453},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000331949000015},
doi = {10.1002/adhm.201300062},
url = {https://juser.fz-juelich.de/record/139343},
}