000014049 001__ 14049
000014049 005__ 20200702121545.0
000014049 0247_ $$2pmid$$apmid:21170519
000014049 0247_ $$2DOI$$a10.1007/s00216-010-4575-x
000014049 0247_ $$2WOS$$aWOS:000286599300015
000014049 037__ $$aPreJuSER-14049
000014049 041__ $$aeng
000014049 082__ $$a540
000014049 084__ $$2WoS$$aBiochemical Research Methods
000014049 084__ $$2WoS$$aChemistry, Analytical
000014049 1001_ $$0P:(DE-HGF)0$$aHoffmann, Th.$$b0
000014049 245__ $$aElectrochemistry-mass spectrometry for mechanistic studies and simulation of oxidation processes in the environment
000014049 260__ $$aBerlin$$bSpringer$$c2011
000014049 300__ $$a1859 - 1868
000014049 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000014049 3367_ $$2DataCite$$aOutput Types/Journal article
000014049 3367_ $$00$$2EndNote$$aJournal Article
000014049 3367_ $$2BibTeX$$aARTICLE
000014049 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000014049 3367_ $$2DRIVER$$aarticle
000014049 440_0 $$08664$$aAnalytical and Bioanalytical Chemistry$$v399$$x1618-2642$$y5
000014049 500__ $$aRecord converted from VDB: 12.11.2012
000014049 520__ $$aElectrochemistry (EC) coupled to mass spectrometry (MS) has already been successfully applied to metabolism research for pharmaceutical applications, especially for the oxidation behaviour of drug substances. Xenobiotics (chemicals in the environment) also undergo various conversions; some of which are oxidative reactions. Therefore, EC-MS might be a suitable tool for the investigation of oxidative behaviour of xenobiotics. A further evaluation of this approach to environmental research is presented in the present paper using sulfonamide antibiotics. The results with sulfadiazine showed that EC-MS is a powerful tool for the elucidation of the oxidative degradation mechanism within a short time period. In addition, it was demonstrated that EC-MS can be used as a fast and easy method to model the chemical binding of xenobiotics to soil. The reaction of sulfadiazine with catechol, as a model substance for organic matter in soil, led to the expected chemical structure. Finally, by using EC-MS a first indication was obtained of the persistence of a component under chemical oxidation conditions for the comparison of the oxidative stability of different classes of xenobiotics. Overall, using just a few examples, the study demonstrates that EC-MS can be applied as a versatile tool for mechanistic studies of oxidative degradation pathways of xenobiotics and their possible interaction with soil organic matter as well as their oxidative stability in the environment. Further studies are needed to evaluate the full range of possibilities of the application of EC-MS in environmental research.
000014049 536__ $$0G:(DE-Juel1)FUEK407$$2G:(DE-HGF)$$aTerrestrische Umwelt$$cP24$$x0
000014049 588__ $$aDataset connected to Web of Science, Pubmed
000014049 650_2 $$2MeSH$$aElectrochemistry
000014049 650_2 $$2MeSH$$aMass Spectrometry
000014049 650_2 $$2MeSH$$aOxidation-Reduction
000014049 650_2 $$2MeSH$$aSoil Pollutants: chemistry
000014049 650_2 $$2MeSH$$aXenobiotics: chemistry
000014049 650_7 $$00$$2NLM Chemicals$$aSoil Pollutants
000014049 650_7 $$00$$2NLM Chemicals$$aXenobiotics
000014049 650_7 $$2WoSType$$aJ
000014049 65320 $$2Author$$aDegradation
000014049 65320 $$2Author$$aXenobiotics
000014049 65320 $$2Author$$aEnvironment
000014049 65320 $$2Author$$aElectrochemistry
000014049 65320 $$2Author$$aMass spectrometry
000014049 7001_ $$0P:(DE-Juel1)129471$$aHofmann, D.$$b1$$uFZJ
000014049 7001_ $$0P:(DE-Juel1)129484$$aKlumpp, E.$$b2$$uFZJ
000014049 7001_ $$0P:(DE-Juel1)133844$$aKüppers, S.$$b3$$uFZJ
000014049 773__ $$0PERI:(DE-600)1459122-4$$a10.1007/s00216-010-4575-x$$gVol. 399, p. 1859 - 1868$$p1859 - 1868$$q399<1859 - 1868$$tAnalytical and bioanalytical chemistry$$v399$$x1618-2642$$y2011
000014049 8567_ $$uhttp://dx.doi.org/10.1007/s00216-010-4575-x
000014049 909CO $$ooai:juser.fz-juelich.de:14049$$pVDB$$pVDB:Earth_Environment
000014049 9131_ $$0G:(DE-Juel1)FUEK407$$bErde und Umwelt$$kP24$$lTerrestrische Umwelt$$vTerrestrische Umwelt$$x0
000014049 9132_ $$0G:(DE-HGF)POF3-255$$1G:(DE-HGF)POF3-250$$2G:(DE-HGF)POF3-200$$aDE-HGF$$bMarine, Küsten- und Polare Systeme$$lTerrestrische Umwelt$$vTerrestrial Systems: From Observation to Prediction$$x0
000014049 9141_ $$y2011
000014049 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000014049 9201_ $$0I:(DE-Juel1)ZCH-20090406$$gZCH$$kZCH$$lZentralabteilung für Chemische Analysen$$x0
000014049 9201_ $$0I:(DE-Juel1)IBG-3-20101118$$gIBG$$kIBG-3$$lAgrosphäre$$x1
000014049 970__ $$aVDB:(DE-Juel1)125883
000014049 980__ $$aVDB
000014049 980__ $$aConvertedRecord
000014049 980__ $$ajournal
000014049 980__ $$aI:(DE-Juel1)ZEA-3-20090406
000014049 980__ $$aI:(DE-Juel1)IBG-3-20101118
000014049 980__ $$aUNRESTRICTED
000014049 981__ $$aI:(DE-Juel1)ZEA-3-20090406
000014049 981__ $$aI:(DE-Juel1)IBG-3-20101118
000014049 981__ $$aI:(DE-Juel1)ZCH-20090406