000014230 001__ 14230
000014230 005__ 20210129210605.0
000014230 0247_ $$2pmid$$apmid:21293877
000014230 0247_ $$2DOI$$a10.1007/s00429-011-0301-5
000014230 0247_ $$2WOS$$aWOS:000293924300007
000014230 0247_ $$2altmetric$$aaltmetric:14503822
000014230 037__ $$aPreJuSER-14230
000014230 041__ $$aeng
000014230 082__ $$a610
000014230 084__ $$2WoS$$aAnatomy & Morphology
000014230 084__ $$2WoS$$aNeurosciences
000014230 1001_ $$0P:(DE-HGF)0$$aHerold, C.$$b0
000014230 245__ $$aThe receptor architecture of the pigeons' nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex
000014230 260__ $$aBerlin$$bSpringer$$c2011
000014230 300__ $$a239 - 254
000014230 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000014230 3367_ $$2DataCite$$aOutput Types/Journal article
000014230 3367_ $$00$$2EndNote$$aJournal Article
000014230 3367_ $$2BibTeX$$aARTICLE
000014230 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000014230 3367_ $$2DRIVER$$aarticle
000014230 440_0 $$017221$$aBrain Structure & Function$$v216$$x1863-2653$$y3
000014230 500__ $$aSupported by a grant from the BMBF through the Bernstein Focus Group "Varying Tunes'' to O.G.
000014230 520__ $$aThe avian nidopallium caudolaterale is a multimodal area in the caudal telencephalon that is apparently not homologous to the mammalian prefrontal cortex but serves comparable functions. Here we analyzed binding-site densities of glutamatergic AMPA, NMDA and kainate receptors, GABAergic GABA(A), muscarinic M(1), M(2) and nicotinic (nACh) receptors, noradrenergic α(1) and α(2), serotonergic 5-HT(1A) and dopaminergic D(1)-like receptors using quantitative in vitro receptor autoradiography. We compared the receptor architecture of the pigeons' nidopallial structures, in particular the NCL, with cortical areas Fr2 and Cg1 in rats and prefrontal area BA10 in humans. Our results confirmed that the relative ratios of multiple receptor densities across different nidopallial structures (their "receptor fingerprints") were very similar in shape; however, the absolute binding densities (the "size" of the fingerprints) differed significantly. This finding enables a delineation of the avian NCL from surrounding structures and a further parcellation into a medial and a lateral part as revealed by differences in densities of nACh, M(2), kainate, and 5-HT(1A) receptors. Comparisons of the NCL with the rat and human frontal structures showed differences in the receptor distribution, particularly of the glutamate receptors, but also revealed highly conserved features like the identical densities of GABA(A), M(2), nACh and D(1)-like receptors. Assuming a convergent evolution of avian and mammalian prefrontal areas, our results support the hypothesis that specific neurochemical traits provide the molecular background for higher order processes such as executive functions. The differences in glutamate receptor distributions may reflect species-specific adaptations.
000014230 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
000014230 536__ $$0G:(DE-HGF)POF2-89571$$a89571 - Connectivity and Activity (POF2-89571)$$cPOF2-89571$$fPOF II T$$x1
000014230 588__ $$aDataset connected to Web of Science, Pubmed
000014230 650_2 $$2MeSH$$aAnimals
000014230 650_2 $$2MeSH$$aAutoradiography
000014230 650_2 $$2MeSH$$aColumbidae: anatomy & histology
000014230 650_2 $$2MeSH$$aColumbidae: metabolism
000014230 650_2 $$2MeSH$$aDensitometry
000014230 650_2 $$2MeSH$$aHumans
000014230 650_2 $$2MeSH$$aImage Processing, Computer-Assisted
000014230 650_2 $$2MeSH$$aRats
000014230 650_2 $$2MeSH$$aReceptor, Muscarinic M1: metabolism
000014230 650_2 $$2MeSH$$aReceptor, Muscarinic M2: metabolism
000014230 650_2 $$2MeSH$$aReceptor, Serotonin, 5-HT1A: metabolism
000014230 650_2 $$2MeSH$$aReceptors, AMPA: metabolism
000014230 650_2 $$2MeSH$$aReceptors, Adrenergic: metabolism
000014230 650_2 $$2MeSH$$aReceptors, Dopamine D1: metabolism
000014230 650_2 $$2MeSH$$aReceptors, GABA-A: metabolism
000014230 650_2 $$2MeSH$$aReceptors, Kainic Acid: metabolism
000014230 650_2 $$2MeSH$$aReceptors, N-Methyl-D-Aspartate: metabolism
000014230 650_2 $$2MeSH$$aReceptors, Neurotransmitter: metabolism
000014230 650_2 $$2MeSH$$aReceptors, Nicotinic: metabolism
000014230 650_2 $$2MeSH$$aSpecies Specificity
000014230 650_2 $$2MeSH$$aTelencephalon: anatomy & histology
000014230 650_2 $$2MeSH$$aTelencephalon: metabolism
000014230 650_7 $$00$$2NLM Chemicals$$aReceptor, Muscarinic M1
000014230 650_7 $$00$$2NLM Chemicals$$aReceptor, Muscarinic M2
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, AMPA
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, Adrenergic
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, Dopamine D1
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, GABA-A
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, Kainic Acid
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, N-Methyl-D-Aspartate
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, Neurotransmitter
000014230 650_7 $$00$$2NLM Chemicals$$aReceptors, Nicotinic
000014230 650_7 $$0112692-38-3$$2NLM Chemicals$$aReceptor, Serotonin, 5-HT1A
000014230 650_7 $$2WoSType$$aJ
000014230 65320 $$2Author$$aReceptor autoradiography
000014230 65320 $$2Author$$aPrefrontal cortex
000014230 65320 $$2Author$$aNidopallium caudolaterale
000014230 65320 $$2Author$$aRat
000014230 65320 $$2Author$$aHuman
000014230 65320 $$2Author$$aFr2
000014230 65320 $$2Author$$aCg1
000014230 65320 $$2Author$$aBA10
000014230 65320 $$2Author$$aDopamine
000014230 65320 $$2Author$$aGlutamate
000014230 65320 $$2Author$$aGABA
000014230 7001_ $$0P:(DE-Juel1)VDB1208$$aPalomero-Gallagher, N.$$b1$$uFZJ
000014230 7001_ $$0P:(DE-HGF)0$$aHellmann, B.$$b2
000014230 7001_ $$0P:(DE-HGF)0$$aKröner, S.$$b3
000014230 7001_ $$0P:(DE-HGF)0$$aTheiss, C.$$b4
000014230 7001_ $$0P:(DE-HGF)0$$aGüntükün, O.$$b5
000014230 7001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b6$$uFZJ
000014230 773__ $$0PERI:(DE-600)2303775-1$$a10.1007/s00429-011-0301-5$$gVol. 216, p. 239 - 254$$p239 - 254$$q216<239 - 254$$tBrain structure & function$$v216$$x1863-2653$$y2011
000014230 8567_ $$uhttp://dx.doi.org/10.1007/s00429-011-0301-5
000014230 909CO $$ooai:juser.fz-juelich.de:14230$$pVDB
000014230 9132_ $$0G:(DE-HGF)POF3-571$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vConnectivity and Activity$$x0
000014230 9131_ $$0G:(DE-HGF)POF2-89571$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vConnectivity and Activity$$x1
000014230 9141_ $$y2011
000014230 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000014230 9201_ $$0I:(DE-Juel1)INM-2-20090406$$gINM$$kINM-2$$lMolekulare Organisation des Gehirns$$x0
000014230 970__ $$aVDB:(DE-Juel1)126259
000014230 980__ $$aVDB
000014230 980__ $$aConvertedRecord
000014230 980__ $$ajournal
000014230 980__ $$aI:(DE-Juel1)INM-2-20090406
000014230 980__ $$aUNRESTRICTED