% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Steinberg:14635,
      author       = {Steinberg, S. and Mors, O. and Borglum, A.D. and
                      Gustafsson, O. and Werge, T. and Mortensen, P.B. and
                      Andreassen, O.A. and Sigurdsson, E. and Thorgeirsson, T.E.
                      and Böttcher, Y. and Olason, P. and Ophoff, R.A. and
                      Cichon, S. and Gudjorsdottir, I.H. and Pietiläinen, O.P.
                      and Nyegaard, M. and Tuulio-Henriksson, A. and Ingason, A.
                      and Hansen, T. and Athansiu, L. and Luvisaari, J. and
                      Lonnqvist, J. and Paunio, T. and Hartmann, A. and Jürgens,
                      G. and Nordentoft, M. and Hougaard, D. and Norgaard-Pdersen,
                      B. and Breuer, R. and Möller, J.H. and Giegling, I. and
                      Glenthoj, B. and Rasmussen, H.B. and Mattheisen, M. and
                      Bitter, I. and Rethelyi, J.M. and Sigundsson, T. and
                      Fossdal, R. and Thorsteinsdottir, U. and Ruggeri, M. and
                      Tosato, S. and Strengman, E. and GOUP Kiemeney, L.A. and
                      Melle, I. and Djurovic, S. and Abramova, L. and Kaleda, V.
                      and Walshe, M. and Bramon, E. and Vassos, E. and Li, T. and
                      Fraser, G. and Walker, N. and Toulopoulou, T. and Yoon, J.
                      and Freimer, N.B. and Cantor, R.M. and Murray, R. and Kong,
                      A. and Golimbet, V. and Jönsson, E.G. and Terenius, L. and
                      Agartz, I. and Petursson, H. and Nöthen, M.M. and
                      Rietschel, M. and Peltonen, L. and Rujescu, D. and Collier,
                      D.A. and Stefansson, H. and St Clair, D. and Stefansson, K.},
      title        = {{E}xpanding the range of {ZNF}804{A} variants conferring
                      risk of psychosis},
      journal      = {Molecular psychiatry},
      volume       = {16},
      issn         = {1359-4184},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {PreJuSER-14635},
      pages        = {59 - 66},
      year         = {2011},
      note         = {We thank the subjects, their families and the recruitment
                      center staff. This work was supported by the European Union
                      (LSHM-CT-2006-037761 (Project SGENE), PIAP-GA-2008-218251
                      (Project PsychGene) and HEALTH-F2-2009-223423 (Project
                      PsychCNVs)), the National Genomic Network (NGFN-2) of the
                      German Federal Ministry of Education and Research (BMBF),
                      the National Institute of Mental Health (R01 MH078075), the
                      Center of Excellence for Complex Disease Genetics of the
                      Academy of Finland (Grants 213506, 129680) and the
                      Biocentrum Helsinki Foundation and Research Program for
                      Molecular Medicine, Faculty of Medicine, University of
                      Helsinki.},
      abstract     = {A trio of genome-wide association studies recently reported
                      sequence variants at three loci to be significantly
                      associated with schizophrenia. No sequence polymorphism had
                      been unequivocally (P<5 × 10(-8)) associated with
                      schizophrenia earlier. However, one variant, rs1344706[T],
                      had come very close. This polymorphism, located in an intron
                      of ZNF804A, was reported to associate with schizophrenia
                      with a P-value of 1.6 × 10(-7), and with psychosis
                      (schizophrenia plus bipolar disorder) with a P-value of 1.0
                      × 10(-8). In this study, using 5164 schizophrenia cases and
                      20,709 controls, we replicated the association with
                      schizophrenia (odds ratio OR = 1.08, P = 0.0029) and, by
                      adding bipolar disorder patients, we also confirmed the
                      association with psychosis (added N = 609, OR = 1.09, P =
                      0.00065). Furthermore, as it has been proposed that variants
                      such as rs1344706[T]-common and with low relative risk-may
                      also serve to identify regions harboring less common,
                      higher-risk susceptibility alleles, we searched ZNF804A for
                      large copy number variants (CNVs) in 4235 psychosis
                      patients, 1173 patients with other psychiatric disorders and
                      39,481 controls. We identified two CNVs including at least
                      part of ZNF804A in psychosis patients and no ZNF804A CNVs in
                      controls (P = 0.013 for association with psychosis). In
                      addition, we found a ZNF804A CNV in an anxiety patient (P =
                      0.0016 for association with the larger set of psychiatric
                      disorders).},
      keywords     = {Anxiety Disorders: genetics / Bipolar Disorder: genetics /
                      Case-Control Studies / DNA Copy Number Variations: genetics
                      / Genetic Predisposition to Disease / Genome-Wide
                      Association Study / Humans / Kruppel-Like Transcription
                      Factors: genetics / Reference Values / Schizophrenia:
                      genetics / Kruppel-Like Transcription Factors (NLM
                      Chemicals) / ZNF804A protein, human (NLM Chemicals) / J
                      (WoSType)},
      cin          = {INM-1},
      ddc          = {610},
      cid          = {I:(DE-Juel1)INM-1-20090406},
      pnm          = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
                      89571 - Connectivity and Activity (POF2-89571) / PSYCHGENE -
                      Copy Number Variation and Endophenotypes in Psychiatric
                      Disorders (218251) / PSYCHCNVS - Copy number variations
                      conferring risk of psychiatric disorders in children
                      (223423)},
      pid          = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571 /
                      G:(EU-Grant)218251 / G:(EU-Grant)223423},
      shelfmark    = {Biochemistry $\&$ Molecular Biology / Neurosciences /
                      Psychiatry},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:20048749},
      pmc          = {pmc:PMC3242031},
      UT           = {WOS:000285546400007},
      doi          = {10.1038/mp.2009.149},
      url          = {https://juser.fz-juelich.de/record/14635},
}