000014893 001__ 14893
000014893 005__ 20210129210617.0
000014893 0247_ $$2pmid$$apmid:21520346
000014893 0247_ $$2DOI$$a10.1002/hbm.21272
000014893 0247_ $$2WOS$$aWOS:000302533100008
000014893 0247_ $$2altmetric$$aaltmetric:685302
000014893 037__ $$aPreJuSER-14893
000014893 041__ $$aeng
000014893 082__ $$a610
000014893 1001_ $$0P:(DE-HGF)0$$aSarfeld, A.S.$$b0
000014893 245__ $$aConvergence of human brain mapping tools: Neuronavigated TMS parameters and fMRI activity in the hand motor area
000014893 260__ $$aNew York, NY$$bWiley-Liss$$c2012
000014893 300__ $$a1107 - 11023
000014893 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000014893 3367_ $$2DataCite$$aOutput Types/Journal article
000014893 3367_ $$00$$2EndNote$$aJournal Article
000014893 3367_ $$2BibTeX$$aARTICLE
000014893 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000014893 3367_ $$2DRIVER$$aarticle
000014893 440_0 $$02398$$aHuman Brain Mapping$$v33$$x1065-9471$$y5
000014893 500__ $$aRecord converted from VDB: 12.11.2012
000014893 520__ $$aFunctional magnetic resonance imaging (fMRI) and transcranial magnetic stimulation (TMS) are well-established tools for investigating the human motor system in-vivo. We here studied the relationship between movement-related fMRI signal changes in the primary motor cortex (M1) and electrophysiological properties of the hand motor area assessed with neuronavigated TMS in 17 healthy subjects. The voxel showing the highest task-related BOLD response in the left hand motor area during right hand movements was identified for each individual subject. This fMRI peak voxel in M1 served as spatial target for coil positioning during neuronavigated TMS. We performed correlation analyses between TMS parameters, BOLD signal estimates and effective connectivity parameters of M1 assessed with dynamic causal modeling (DCM). The results showed a negative correlation between the movement-related BOLD signal in left M1 and resting as well as active motor threshold (MT) obtained for left M1. The DCM analysis revealed that higher excitability of left M1 was associated with a stronger coupling between left supplementary motor area (SMA) and M1. Furthermore, BOLD activity in left M1 correlated with ipsilateral silent period (ISP), i.e. the stronger the task-related BOLD response in left M1, the higher interhemispheric inhibition effects targeting right M1. DCM analyses revealed a positive correlation between the coupling of left SMA with left M1 and the duration of ISP. The data show that TMS parameters assessed for the hand area of M1 do not only reflect the intrinsic properties at the stimulation site but also interactions with remote areas in the human motor system.
000014893 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
000014893 536__ $$0G:(DE-HGF)POF2-89572$$a89572 - (Dys-)function and Plasticity (POF2-89572)$$cPOF2-89572$$fPOF II T$$x1
000014893 588__ $$aDataset connected to Pubmed
000014893 7001_ $$0P:(DE-HGF)0$$aDiekhoff, S.$$b1
000014893 7001_ $$0P:(DE-HGF)0$$aWang, L.E.$$b2
000014893 7001_ $$0P:(DE-HGF)0$$aLiuzzi, G.$$b3
000014893 7001_ $$0P:(DE-HGF)0$$aUludag, K.$$b4
000014893 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, S.B.$$b5$$uFZJ
000014893 7001_ $$0P:(DE-Juel1)131720$$aFink, G.R.$$b6$$uFZJ
000014893 7001_ $$0P:(DE-HGF)0$$aGrefkes, C.$$b7
000014893 773__ $$0PERI:(DE-600)1492703-2$$a10.1002/hbm.21272$$gVol. 33, p. 1107 - 11023$$p1107 - 11023$$q33<1107 - 11023$$tHuman brain mapping$$v33$$x1065-9471$$y2012
000014893 8567_ $$uhttp://dx.doi.org/10.1002/hbm.21272
000014893 909CO $$ooai:juser.fz-juelich.de:14893$$pVDB
000014893 915__ $$0StatID:(DE-HGF)0010$$2StatID$$aJCR/ISI refereed
000014893 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR
000014893 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded
000014893 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection
000014893 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List
000014893 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS
000014893 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline
000014893 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database
000014893 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz
000014893 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences
000014893 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews
000014893 9141_ $$y2012
000014893 9132_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0
000014893 9131_ $$0G:(DE-HGF)POF2-89572$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$v(Dys-)function and Plasticity$$x1
000014893 9201_ $$0I:(DE-Juel1)INM-1-20090406$$gINM$$kINM-1$$lStrukturelle und funktionelle Organisation des Gehirns$$x1
000014893 9201_ $$0I:(DE-Juel1)INM-3-20090406$$gINM$$kINM-3$$lKognitive Neurowissenschaften$$x2
000014893 970__ $$aVDB:(DE-Juel1)127390
000014893 980__ $$aVDB
000014893 980__ $$aConvertedRecord
000014893 980__ $$ajournal
000014893 980__ $$aI:(DE-Juel1)INM-1-20090406
000014893 980__ $$aI:(DE-Juel1)INM-3-20090406
000014893 980__ $$aUNRESTRICTED
000014893 981__ $$aI:(DE-Juel1)INM-3-20090406