000014894 001__ 14894
000014894 005__ 20210129210618.0
000014894 0247_ $$2pmid$$apmid:21335939
000014894 0247_ $$2DOI$$a10.1159/000323671
000014894 0247_ $$2WOS$$aWOS:000290093800002
000014894 0247_ $$2Handle$$a2128/7289
000014894 0247_ $$2altmetric$$aaltmetric:21805860
000014894 037__ $$aPreJuSER-14894
000014894 041__ $$aeng
000014894 082__ $$a150
000014894 084__ $$2WoS$$aBehavioral Sciences
000014894 084__ $$2WoS$$aNeurosciences
000014894 084__ $$2WoS$$aZoology
000014894 1001_ $$0P:(DE-HGF)0$$aSmaers, J.B.$$b0
000014894 245__ $$aPrimate Prefrontal Cortex Evolution: Human Brains are the Extreme of a Lateralized Ape Trend
000014894 260__ $$aBasel$$bKarger$$c2011
000014894 300__ $$a67 - 78
000014894 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
000014894 3367_ $$2DataCite$$aOutput Types/Journal article
000014894 3367_ $$00$$2EndNote$$aJournal Article
000014894 3367_ $$2BibTeX$$aARTICLE
000014894 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000014894 3367_ $$2DRIVER$$aarticle
000014894 440_0 $$011863$$aBrain, Behavior and Evolution$$v77$$x0006-8977
000014894 500__ $$aWe would like to thank Axel Schleicher and John R. Skoyles for useful comments and discussion and Hartmut Mohlberg for making images with the delineation of the motor cortex available from the Julich/Dusseldorf brain atlas. For training in phylogenetic comparative methods, we thank the AnthroTree Workshop (supported by NSF BCS-0923791). This work was supported by the EC FP6 HANDTOMOUTH project (contract No. 29065).
000014894 520__ $$aThe prefrontal cortex is commonly associated with cognitive capacities related to human uniqueness: purposeful actions towards higher-level goals, complex social information processing, introspection, and language. Comparative investigations of the prefrontal cortex may thus shed more light on the neural underpinnings of what makes us human. Using histological data from 19 anthropoid primate species (6 apes including humans and 13 monkeys), we investigate cross-species relative size changes along the anterior (prefrontal) and posterior (motor) axes of the cytoarchitectonically defined frontal lobe in both hemispheres. Results reveal different scaling coefficients in the left versus right prefrontal hemisphere, suggest that the primary factor underlying the evolution of primate brain architecture is left hemispheric prefrontal hyperscaling, and indicate that humans are the extreme of a left prefrontal ape specialization in relative white to grey matter volume. These results demonstrate a neural adaptive shift distinguishing the ape from the monkey radiation possibly related to a cognitive grade shift between (great) apes and other primates.
000014894 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
000014894 536__ $$0G:(DE-HGF)POF2-89571$$a89571 - Connectivity and Activity (POF2-89571)$$cPOF2-89571$$fPOF II T$$x1
000014894 588__ $$aDataset connected to Web of Science, Pubmed
000014894 65320 $$2Author$$aPrefrontal cortex
000014894 65320 $$2Author$$aNeocortex
000014894 65320 $$2Author$$aLateralization
000014894 65320 $$2Author$$aAsymmetry
000014894 65320 $$2Author$$aPrimate
000014894 65320 $$2Author$$aAllometry
000014894 650_2 $$2MeSH$$aAnimals
000014894 650_2 $$2MeSH$$aBiological Evolution
000014894 650_2 $$2MeSH$$aFunctional Laterality: physiology
000014894 650_2 $$2MeSH$$aHominidae: anatomy & histology
000014894 650_2 $$2MeSH$$aHominidae: growth & development
000014894 650_2 $$2MeSH$$aHumans
000014894 650_2 $$2MeSH$$aMale
000014894 650_2 $$2MeSH$$aPrefrontal Cortex: anatomy & histology
000014894 650_2 $$2MeSH$$aPrefrontal Cortex: growth & development
000014894 650_7 $$2WoSType$$aJ
000014894 7001_ $$0P:(DE-HGF)0$$aSteele, J.$$b1
000014894 7001_ $$0P:(DE-HGF)0$$aCase, C.R.$$b2
000014894 7001_ $$0P:(DE-HGF)0$$aCowper, A.$$b3
000014894 7001_ $$0P:(DE-Juel1)131631$$aAmunts, K.$$b4$$uFZJ
000014894 7001_ $$0P:(DE-Juel1)131714$$aZilles, K.$$b5$$uFZJ
000014894 773__ $$0PERI:(DE-600)1482032-8$$a10.1159/000323671$$gVol. 77, p. 67 - 78$$p67 - 78$$q77<67 - 78$$tBrain, behavior and evolution$$v77$$x0006-8977$$y2011
000014894 8567_ $$uhttp://dx.doi.org/10.1159/000323671
000014894 8564_ $$uhttps://juser.fz-juelich.de/record/14894/files/FZJ-14894.pdf$$yPublished under German "Allianz" Licensing conditions on 2011-04-01. Available in OpenAccess from 2012-04-01$$zPublished final document.
000014894 8564_ $$uhttps://juser.fz-juelich.de/record/14894/files/FZJ-14894.jpg?subformat=icon-1440$$xicon-1440
000014894 8564_ $$uhttps://juser.fz-juelich.de/record/14894/files/FZJ-14894.jpg?subformat=icon-180$$xicon-180
000014894 8564_ $$uhttps://juser.fz-juelich.de/record/14894/files/FZJ-14894.jpg?subformat=icon-640$$xicon-640
000014894 909CO $$ooai:juser.fz-juelich.de:14894$$pdnbdelivery$$pVDB$$pdriver$$popen_access$$popenaire
000014894 915__ $$0StatID:(DE-HGF)0010$$aJCR/ISI refereed
000014894 915__ $$0StatID:(DE-HGF)0520$$2StatID$$aAllianz-OA
000014894 9141_ $$y2011
000014894 9132_ $$0G:(DE-HGF)POF3-571$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$vConnectivity and Activity$$x0
000014894 9131_ $$0G:(DE-HGF)POF2-89571$$1G:(DE-HGF)POF3-890$$2G:(DE-HGF)POF3-800$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bProgrammungebundene Forschung$$lohne Programm$$vConnectivity and Activity$$x1
000014894 9201_ $$0I:(DE-Juel1)INM-2-20090406$$gINM$$kINM-2$$lMolekulare Organisation des Gehirns$$x0
000014894 9201_ $$0I:(DE-Juel1)INM-1-20090406$$gINM$$kINM-1$$lStrukturelle und funktionelle Organisation des Gehirns$$x1
000014894 970__ $$aVDB:(DE-Juel1)127391
000014894 980__ $$aVDB
000014894 980__ $$aConvertedRecord
000014894 980__ $$ajournal
000014894 980__ $$aI:(DE-Juel1)INM-2-20090406
000014894 980__ $$aI:(DE-Juel1)INM-1-20090406
000014894 980__ $$aUNRESTRICTED
000014894 980__ $$aJUWEL
000014894 980__ $$aFullTexts
000014894 9801_ $$aFullTexts
000014894 981__ $$aI:(DE-Juel1)INM-1-20090406