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@ARTICLE{Smaers:14894,
author = {Smaers, J.B. and Steele, J. and Case, C.R. and Cowper, A.
and Amunts, K. and Zilles, K.},
title = {{P}rimate {P}refrontal {C}ortex {E}volution: {H}uman
{B}rains are the {E}xtreme of a {L}ateralized {A}pe {T}rend},
journal = {Brain, behavior and evolution},
volume = {77},
issn = {0006-8977},
address = {Basel},
publisher = {Karger},
reportid = {PreJuSER-14894},
pages = {67 - 78},
year = {2011},
note = {We would like to thank Axel Schleicher and John R. Skoyles
for useful comments and discussion and Hartmut Mohlberg for
making images with the delineation of the motor cortex
available from the Julich/Dusseldorf brain atlas. For
training in phylogenetic comparative methods, we thank the
AnthroTree Workshop (supported by NSF BCS-0923791). This
work was supported by the EC FP6 HANDTOMOUTH project
(contract No. 29065).},
abstract = {The prefrontal cortex is commonly associated with cognitive
capacities related to human uniqueness: purposeful actions
towards higher-level goals, complex social information
processing, introspection, and language. Comparative
investigations of the prefrontal cortex may thus shed more
light on the neural underpinnings of what makes us human.
Using histological data from 19 anthropoid primate species
(6 apes including humans and 13 monkeys), we investigate
cross-species relative size changes along the anterior
(prefrontal) and posterior (motor) axes of the
cytoarchitectonically defined frontal lobe in both
hemispheres. Results reveal different scaling coefficients
in the left versus right prefrontal hemisphere, suggest that
the primary factor underlying the evolution of primate brain
architecture is left hemispheric prefrontal hyperscaling,
and indicate that humans are the extreme of a left
prefrontal ape specialization in relative white to grey
matter volume. These results demonstrate a neural adaptive
shift distinguishing the ape from the monkey radiation
possibly related to a cognitive grade shift between (great)
apes and other primates.},
keywords = {Animals / Biological Evolution / Functional Laterality:
physiology / Hominidae: anatomy $\&$ histology / Hominidae:
growth $\&$ development / Humans / Male / Prefrontal Cortex:
anatomy $\&$ histology / Prefrontal Cortex: growth $\&$
development / J (WoSType)},
cin = {INM-2 / INM-1},
ddc = {150},
cid = {I:(DE-Juel1)INM-2-20090406 / I:(DE-Juel1)INM-1-20090406},
pnm = {Funktion und Dysfunktion des Nervensystems (FUEK409) /
89571 - Connectivity and Activity (POF2-89571)},
pid = {G:(DE-Juel1)FUEK409 / G:(DE-HGF)POF2-89571},
shelfmark = {Behavioral Sciences / Neurosciences / Zoology},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:21335939},
UT = {WOS:000290093800002},
doi = {10.1159/000323671},
url = {https://juser.fz-juelich.de/record/14894},
}