000150347 001__ 150347
000150347 005__ 20210129213143.0
000150347 0247_ $$2DOI$$a10.1044/2014_JSLHR-S-13-0155
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000150347 1001_ $$0P:(DE-HGF)0$$aMücke, D.$$b0$$eCorresponding author
000150347 245__ $$aThe Effect of Deep Brain Stimulation on the Speech Motor System
000150347 260__ $$aRockville, Md.$$bAmerican Speech-Language-Hearing Association$$c2014
000150347 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1411038487_17272
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000150347 520__ $$aPurpose: Chronic deep brain stimulation of the nucleus ventralis intermedius is an effective treatment for individuals with medication-resistant essential tremor. However, these individuals report that stimulation has a deleterious effect on their speech. The present study investigates one important factor leading to these effects: the coordination of oral and glottal articulation.Method: Sixteen native-speaking German adults with essential tremor, between 26 and 86 years old, with and without chronic deep brain stimulation of the nucleus ventralis intermedius and 12 healthy, age-matched subjects were recorded performing a fast syllable repetition task (/papapa/, /tatata/, /kakaka/). Syllable duration and voicing-to-syllable ratio as well as parameters related directly to consonant production, voicing during constriction, and frication during constriction were measured.Results: Voicing during constriction was greater in subjects with essential tremor than in controls, indicating a perseveration of voicing into the voiceless consonant. Stimulation led to fewer voiceless intervals (voicing-to-syllable ratio), indicating a reduced degree of glottal abduction during the entire syllable cycle. Stimulation also induced incomplete oral closures (frication during constriction), indicating imprecise oral articulation.Conclusion: The detrimental effect of stimulation on the speech motor system can be quantified using acoustic measures at the subsyllabic level.
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000150347 7001_ $$0P:(DE-HGF)0$$aBecker, J.$$b1
000150347 7001_ $$0P:(DE-Juel1)131613$$aBarbe, Michael$$b2$$ufzj
000150347 7001_ $$0P:(DE-HGF)0$$aMeister, I.$$b3
000150347 7001_ $$0P:(DE-HGF)0$$aLiebhart, L.$$b4
000150347 7001_ $$0P:(DE-HGF)0$$aRöttger, T. B.$$b5
000150347 7001_ $$0P:(DE-HGF)0$$aDembek, T.$$b6
000150347 7001_ $$0P:(DE-HGF)0$$aTimmermann, L.$$b7
000150347 7001_ $$0P:(DE-HGF)0$$aGrice, M.$$b8
000150347 773__ $$0PERI:(DE-600)2070420-3$$a10.1044/2014_JSLHR-S-13-0155$$p1206-1218$$tJournal of speech, language, and hearing research$$v57$$x1558-9102$$y2014
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000150347 9141_ $$y2014
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