001     150347
005     20210129213143.0
024 7 _ |2 DOI
|a 10.1044/2014_JSLHR-S-13-0155
024 7 _ |a WOS:000348198000006
|2 WOS
037 _ _ |a FZJ-2014-00417
082 _ _ |a 400
100 1 _ |0 P:(DE-HGF)0
|a Mücke, D.
|b 0
|e Corresponding author
245 _ _ |a The Effect of Deep Brain Stimulation on the Speech Motor System
260 _ _ |a Rockville, Md.
|b American Speech-Language-Hearing Association
|c 2014
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1411038487_17272
|2 PUB:(DE-HGF)
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|0 0
|2 EndNote
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a article
|2 DRIVER
520 _ _ |a Purpose: Chronic deep brain stimulation of the nucleus ventralis intermedius is an effective treatment for individuals with medication-resistant essential tremor. However, these individuals report that stimulation has a deleterious effect on their speech. The present study investigates one important factor leading to these effects: the coordination of oral and glottal articulation.Method: Sixteen native-speaking German adults with essential tremor, between 26 and 86 years old, with and without chronic deep brain stimulation of the nucleus ventralis intermedius and 12 healthy, age-matched subjects were recorded performing a fast syllable repetition task (/papapa/, /tatata/, /kakaka/). Syllable duration and voicing-to-syllable ratio as well as parameters related directly to consonant production, voicing during constriction, and frication during constriction were measured.Results: Voicing during constriction was greater in subjects with essential tremor than in controls, indicating a perseveration of voicing into the voiceless consonant. Stimulation led to fewer voiceless intervals (voicing-to-syllable ratio), indicating a reduced degree of glottal abduction during the entire syllable cycle. Stimulation also induced incomplete oral closures (frication during constriction), indicating imprecise oral articulation.Conclusion: The detrimental effect of stimulation on the speech motor system can be quantified using acoustic measures at the subsyllabic level.
536 _ _ |a 333 - Pathophysiological Mechanisms of Neurological and Psychiatric Diseases (POF2-333)
|0 G:(DE-HGF)POF2-333
|c POF2-333
|f POF II
|x 0
536 _ _ |a 89572 - (Dys-)function and Plasticity (POF2-89572)
|0 G:(DE-HGF)POF2-89572
|c POF2-89572
|x 1
|f POF II T
700 1 _ |0 P:(DE-HGF)0
|a Becker, J.
|b 1
700 1 _ |0 P:(DE-Juel1)131613
|a Barbe, Michael
|b 2
|u fzj
700 1 _ |0 P:(DE-HGF)0
|a Meister, I.
|b 3
700 1 _ |0 P:(DE-HGF)0
|a Liebhart, L.
|b 4
700 1 _ |0 P:(DE-HGF)0
|a Röttger, T. B.
|b 5
700 1 _ |0 P:(DE-HGF)0
|a Dembek, T.
|b 6
700 1 _ |0 P:(DE-HGF)0
|a Timmermann, L.
|b 7
700 1 _ |0 P:(DE-HGF)0
|a Grice, M.
|b 8
773 _ _ |0 PERI:(DE-600)2070420-3
|a 10.1044/2014_JSLHR-S-13-0155
|p 1206-1218
|t Journal of speech, language, and hearing research
|v 57
|x 1558-9102
|y 2014
909 C O |o oai:juser.fz-juelich.de:150347
|p VDB
910 1 _ |0 I:(DE-588b)5008462-8
|6 P:(DE-Juel1)131613
|a Forschungszentrum Jülich GmbH
|b 2
|k FZJ
913 2 _ |a DE-HGF
|b POF III
|l Key Technologies
|1 G:(DE-HGF)POF3-570
|0 G:(DE-HGF)POF3-572
|2 G:(DE-HGF)POF3-500
|v Decoding the Human Brain
|x 0
913 1 _ |a DE-HGF
|b Gesundheit
|l Funktion und Dysfunktion des Nervensystems
|1 G:(DE-HGF)POF2-330
|0 G:(DE-HGF)POF2-333
|2 G:(DE-HGF)POF2-300
|v Pathophysiological Mechanisms of Neurological and Psychiatric Diseases
|x 0
|4 G:(DE-HGF)POF
|3 G:(DE-HGF)POF2
913 1 _ |a DE-HGF
|0 G:(DE-HGF)POF2-89572
|v (Dys-)function and Plasticity
|x 1
|4 G:(DE-HGF)POF
|1 G:(DE-HGF)POF3-890
|3 G:(DE-HGF)POF3
|2 G:(DE-HGF)POF3-800
|b Programmungebundene Forschung
|l ohne Programm
914 1 _ |y 2014
915 _ _ |a Peer review unknown
|0 StatID:(DE-HGF)0040
|2 StatID
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
915 _ _ |a WoS
|0 StatID:(DE-HGF)0111
|2 StatID
|b Science Citation Index Expanded
915 _ _ |a WoS
|0 StatID:(DE-HGF)0130
|2 StatID
|b Social Sciences Citation Index
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Thomson Reuters Master Journal List
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0310
|2 StatID
|b NCBI Molecular Biology Database
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1020
|2 StatID
|b Current Contents - Social and Behavioral Sciences
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
920 1 _ |0 I:(DE-Juel1)INM-3-20090406
|k INM-3
|l Kognitive Neurowissenschaften
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-Juel1)INM-3-20090406
980 _ _ |a UNRESTRICTED


LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21