000150579 001__ 150579
000150579 005__ 20210129213223.0
000150579 0247_ $$2doi$$a10.1007/s11682-013-9269-5
000150579 0247_ $$2pmid$$apmid:24399358
000150579 0247_ $$2ISSN$$a1931-7565
000150579 0247_ $$2ISSN$$a1931-7557
000150579 0247_ $$2WOS$$aWOS:000335765700003
000150579 0247_ $$2altmetric$$aaltmetric:2032687
000150579 037__ $$aFZJ-2014-00628
000150579 041__ $$aENG
000150579 082__ $$a150
000150579 1001_ $$0P:(DE-HGF)0$$aThompson, Paul M.$$b0$$eCorresponding author
000150579 245__ $$aThe ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
000150579 260__ $$aNew York, NY [u.a.]$$bSpringer$$c2014
000150579 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1401275698_5152
000150579 3367_ $$2DataCite$$aOutput Types/Journal article
000150579 3367_ $$00$$2EndNote$$aJournal Article
000150579 3367_ $$2BibTeX$$aARTICLE
000150579 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000150579 3367_ $$2DRIVER$$aarticle
000150579 520__ $$aThe Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.
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000150579 588__ $$aDataset connected to CrossRef, juser.fz-juelich.de, PubMed,
000150579 7001_ $$0P:(DE-HGF)0$$aStein, Jason L$$b1
000150579 7001_ $$0P:(DE-HGF)0$$aMedland, Sarah E$$b2
000150579 7001_ $$0P:(DE-HGF)0$$aHibar, Derrek P$$b3
000150579 7001_ $$0P:(DE-HGF)0$$aVasquez, Alejandro Arias$$b4
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