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@ARTICLE{Kuzmanovic:150615,
author = {Kuzmanovic, Bojana and Schilbach, L. and Georgescu, A. L.
and Kockler, H. and Santos, N. S. and Shah, N. J. and Bente,
G. and Fink, G. R. and Vogeley, K.},
title = {{D}issociating animacy processing in high-functioning
autism: neural correlates of stimulus properties and
subjective ratings.},
journal = {Social neuroscience},
volume = {9},
number = {3},
issn = {1747-0927},
address = {New York [u.a.]},
publisher = {Psychology Press},
reportid = {FZJ-2014-00664},
pages = {309-325},
year = {2014},
abstract = {When movements indicate meaningful actions, even
nonbiological objects induce the impression of “having a
mind” or animacy. This basic social ability was
investigated in adults with high-functioning autism (HFA, n
= 13, and matched controls, n = 13) by systematically
varying motion properties of simple geometric shapes.
Critically, trial-by-trial variations of (1) motion
complexity of stimuli, and of (2) participants’ individual
animacy ratings were separately correlated with neural
activity to dissociate cognitive strategies relying more
closely on stimulus analysis vs. subjective experience.
Increasing motion complexity did not yield any significant
group differences, and in both groups, it correlated with
neural activity in regions involved in perceptual and
evaluative processing, including the ventral medial
prefrontal cortex (mPFC), superior temporal gyrus (STG) and
posterior cingulate cortex (PCC). In contrast, although
there were no significant behavioral differences between the
groups, increasing animacy ratings correlated with neural
activity in the insula, STG, amygdala, dorsal mPFC and PCC
more strongly in controls than in HFA. These results
indicate that in HFA the evaluation of stimulus properties
cuing for animacy is intact, while increasing subjective
ratings do not seem to be robustly related to social
processing, including spontaneous mental state inferences
and experience of salience},
cin = {INM-3 / INM-4 / INM-8},
ddc = {610},
cid = {I:(DE-Juel1)INM-3-20090406 / I:(DE-Juel1)INM-4-20090406 /
I:(DE-Juel1)INM-8-20090406},
pnm = {333 - Pathophysiological Mechanisms of Neurological and
Psychiatric Diseases (POF2-333) / 89572 - (Dys-)function and
Plasticity (POF2-89572)},
pid = {G:(DE-HGF)POF2-333 / G:(DE-HGF)POF2-89572},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000334067000011},
pubmed = {pmid:24512520},
doi = {10.1080/17470919.2014.886618},
url = {https://juser.fz-juelich.de/record/150615},
}