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Conference Presentation (After Call) | FZJ-2014-00942 |
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2013
Abstract: Simultaneous stimulation and recording of retinal nerve cells with penetrating three dimensional multi-electrode arrays on a localized area is a demanding challenge in next generation retina implant research. Within the scope of this research we developed a device to stimulate a network of bi-polar cells and record retinal ganglion cells with a slight time gap to overcome long recording dead times and switching artifacts in common stimulation- and recording systems. The device contains a four channel stimulator capable of pushing arbitrary bi-polar charges into the tissue and a 16 channel commercial electrophysiology interface chip. The device is a miniaturized front-end for our former developed embedded wireless communicating sensor node. First tests in in-vitro retina slices from adult rat with our device show reliable recordings of ganglia cell activity below 1ms after the bi-polar cell stimulation.
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