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000150915 1001_ $$0P:(DE-Juel1)138266$$aSchrader, Tobias$$b0$$eCorresponding author$$ufzj
000150915 245__ $$aBIODIFF: First installations anddetector concepts
000150915 260__ $$c2010
000150915 300__ $$a2
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000150915 520__ $$aIn collaboration between the ForschungszentrumJülich (FZJ) and the ForschungsneutronenquelleHeinz Maier-Leibnitz (FRM II) a single crystaldiffractometer optimised for crystals with largeunit cells is being built. Its scientific focus will bethe determination of the exact location and bond-ing properties of hydrogen atoms in protein orDNA crystals. With this information the hydrationpattern of proteins can be studied, the protona-tion state of critical amino acid side chains canbe determined and even dynamical informationcan be obtained by determining the hydrogen-deuterium exchange of the protein backbone. Inorder to achieve these results two detector con-cepts are foreseen: a) an image plate detectorcovering a large solid angle and b) a neutronscintillator imaged onto a CCD-camera providinga fast read out for a timely alignment of the crys-tals and additional detection abilities.
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000150915 7001_ $$0P:(DE-HGF)0$$aOstermann, Andreas$$b1
000150915 7001_ $$0P:(DE-Juel1)133702$$aLaatsch, Bernhard$$b2
000150915 7001_ $$0P:(DE-HGF)0$$aJüttner, Philipp$$b3
000150915 7001_ $$0P:(DE-Juel1)130849$$aMonkenbusch, Michael$$b4$$ufzj
000150915 7001_ $$0P:(DE-HGF)0$$aPetry, Winfried$$b5
000150915 7001_ $$0P:(DE-Juel1)130917$$aRichter, Dieter$$b6$$ufzj
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