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@ARTICLE{Seibert:151179,
      author       = {Seibert, M. Marvin and Ekeberg, Tomas and Maia, Filipe R.
                      N. C. and Svenda, Martin and Andreasson, Jakob and Jönsson,
                      Olof and Odić, Duško and Iwan, Bianca and Rocker, Andrea
                      and Westphal, Daniel and Hantke, Max and DePonte, Daniel P.
                      and Barty, Anton and Schulz, Joachim and Gumprecht, Lars and
                      Coppola, Nicola and Aquila, Andrew and Liang, Mengning and
                      White, Thomas A. and Martin, Andrew and Caleman, Carl and
                      Stern, Stephan and Abergel, Chantal and Seltzer, Virginie
                      and Claverie, Jean-Michel and Bostedt, Christoph and Bozek,
                      John D. and Boutet, Sébastien and Miahnahri, A. Alan and
                      Messerschmidt, Marc and Krzywinski, Jacek and Williams,
                      Garth and Hodgson, Keith O. and Bogan, Michael J. and
                      Hampton, Christina Y. and Sierra, Raymond G. and Starodub,
                      Dmitri and Andersson, Inger and Bajt, Saša and Barthelmess,
                      Miriam and Spence, John C. H. and Fromme, Petra and
                      Weierstall, Uwe and Kirian, Richard and Hunter, Mark and
                      Doak, R. Bruce and Marchesini, Stefano and Hau-Riege, Stefan
                      P. and Frank, Matthias and Shoeman, Robert L. and Lomb,
                      Lukas and Epp, Sascha W. and Hartmann, Robert and Rolles,
                      Daniel and Rudenko, Artem and Schmidt, Carlo and Foucar,
                      Lutz and Kimmel, Nils and Holl, Peter and Rudek, Benedikt
                      and Erk, Benjamin and Hömke, André and Reich, Christian
                      and Pietschner, Daniel and Weidenspointner, Georg and
                      Strüder, Lothar and Hauser, Günter and Gorke, Hubert and
                      Ullrich, Joachim and Schlichting, Ilme and Herrmann, Sven
                      and Schaller, Gerhard and Schopper, Florian and Soltau,
                      Heike and Kühnel, Kai-Uwe and Andritschke, Robert and
                      Schröter, Claus-Dieter and Krasniqi, Faton and Bott, Mario
                      and Schorb, Sebastian and Rupp, Daniela and Adolph, Marcus
                      and Gorkhover, Tais and Hirsemann, Helmut and Potdevin,
                      Guillaume and Graafsma, Heinz and Nilsson, Björn and
                      Chapman, Henry N. and Hajdu, Janos},
      title        = {{S}ingle mimivirus particles intercepted and imaged with an
                      {X}-ray laser},
      journal      = {Nature},
      volume       = {470},
      number       = {7332},
      issn         = {1476-4687},
      address      = {London [u.a.]},
      publisher    = {Nature Publising Group78092},
      reportid     = {FZJ-2014-01178},
      pages        = {78 - 81},
      year         = {2011},
      abstract     = {X-ray lasers offer new capabilities in understanding the
                      structure of biological systems, complex materials and
                      matter under extreme conditions1, 2, 3, 4. Very short and
                      extremely bright, coherent X-ray pulses can be used to
                      outrun key damage processes and obtain a single diffraction
                      pattern from a large macromolecule, a virus or a cell before
                      the sample explodes and turns into plasma1. The continuous
                      diffraction pattern of non-crystalline objects permits
                      oversampling and direct phase retrieval2. Here we show that
                      high-quality diffraction data can be obtained with a single
                      X-ray pulse from a non-crystalline biological sample, a
                      single mimivirus particle, which was injected into the
                      pulsed beam of a hard-X-ray free-electron laser, the Linac
                      Coherent Light Source5. Calculations indicate that the
                      energy deposited into the virus by the pulse heated the
                      particle to over 100,000 K after the pulse had left the
                      sample. The reconstructed exit wavefront (image) yielded
                      32-nm full-period resolution in a single exposure and showed
                      no measurable damage. The reconstruction indicates
                      inhomogeneous arrangement of dense material inside the
                      virion. We expect that significantly higher resolutions will
                      be achieved in such experiments with shorter and brighter
                      photon pulses focused to a smaller area. The resolution in
                      such experiments can be further extended for samples
                      available in multiple identical copies.},
      cin          = {ZEA-2},
      ddc          = {070},
      cid          = {I:(DE-Juel1)ZEA-2-20090406},
      pnm          = {531 - Hadron Structure and Dynamics (HSD) (POF2-531)},
      pid          = {G:(DE-HGF)POF2-531},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000286886400037},
      pubmed       = {pmid:21293374},
      doi          = {10.1038/nature09748},
      url          = {https://juser.fz-juelich.de/record/151179},
}