000151505 001__ 151505 000151505 005__ 20210129213513.0 000151505 0247_ $$2doi$$a10.1177/1545968314528067 000151505 0247_ $$2WOS$$aWOS:000346241700005 000151505 0247_ $$2altmetric$$aaltmetric:2510225 000151505 0247_ $$2pmid$$apmid:24743226 000151505 037__ $$aFZJ-2014-01443 000151505 082__ $$a610 000151505 1001_ $$0P:(DE-HGF)0$$aSchnakers, C.$$b0$$eCorresponding author 000151505 245__ $$aImpact of aphasia on consciousness assessment. 000151505 260__ $$aThousand Oaks, Calif.$$bSage$$c2015 000151505 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1418305716_4289 000151505 3367_ $$2DataCite$$aOutput Types/Journal article 000151505 3367_ $$00$$2EndNote$$aJournal Article 000151505 3367_ $$2BibTeX$$aARTICLE 000151505 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000151505 3367_ $$2DRIVER$$aarticle 000151505 520__ $$aBackground. Previous findings suggest that language disorders may occur in severely brain-injured patients and could interfere with behavioral assessments of consciousness. However, no study investigated to what extent language impairment could affect patients’ behavioral responses. Objective. To estimate the impact of receptive and/or productive language impairments on consciousness assessment. Methods. Twenty-four acute and subacute stroke patients with different types of aphasia (global, n = 11; Broca, n = 4; Wernicke, n = 3; anomic, n = 4; mixed, n = 2) were recruited in neurology and neurosurgery units as well as in rehabilitation centers. The Coma Recovery Scale–Revised (CRS-R) was administered. Results. We observed that 25% (6 out of 24) of stroke patients with a diagnosis of aphasia and 54% (6 out of 11) of patients with a diagnosis of global aphasia did not reach the maximal CRS-R total score of 23. An underestimation of the consciousness level was observed in 3 patients with global aphasia who could have been misdiagnosed as being in a minimally conscious state, even in the absence of any documented period of coma. More precisely, lower subscores were observed on the communication, motor, oromotor, and arousal subscales. Conclusion. Consciousness assessment may be complicated by the co-occurrence of severe language deficits. This stresses the importance of developing new tools or identifying items in existing scales, which may allow the detection of language impairment in severely brain-injured patients. 000151505 536__ $$0G:(DE-HGF)POF3-572$$a572 - (Dys-)function and Plasticity (POF3-572)$$cPOF3-572$$fPOF III$$x0 000151505 7001_ $$0P:(DE-HGF)0$$aBessou, H.$$b1 000151505 7001_ $$0P:(DE-HGF)0$$aRubi-Fessen, I.$$b2 000151505 7001_ $$0P:(DE-HGF)0$$aHartmann, A.$$b3 000151505 7001_ $$0P:(DE-Juel1)131720$$aFink, Gereon Rudolf$$b4$$ufzj 000151505 7001_ $$0P:(DE-HGF)0$$aMeister, I.$$b5 000151505 7001_ $$0P:(DE-HGF)0$$aGiacino, J. T.$$b6 000151505 7001_ $$0P:(DE-HGF)0$$aLaureys, S.$$b7 000151505 7001_ $$0P:(DE-HGF)0$$aMajerus, S.$$b8 000151505 773__ $$0PERI:(DE-600)2100545-X$$a10.1177/1545968314528067$$n1$$p41-47$$tNeurorehabilitation and neural repair$$v29$$x1545-9683$$y2015 000151505 909CO $$ooai:juser.fz-juelich.de:151505$$pVDB 000151505 9101_ $$0I:(DE-588b)5008462-8$$6P:(DE-Juel1)131720$$aForschungszentrum Jülich GmbH$$b4$$kFZJ 000151505 9130_ $$0G:(DE-HGF)POF2-333$$1G:(DE-HGF)POF2-330$$2G:(DE-HGF)POF2-300$$aDE-HGF$$bGesundheit$$lFunktion und Dysfunktion des Nervensystems$$vPathophysiological Mechanisms of Neurological and Psychiatric Diseases$$x0 000151505 9130_ $$0G:(DE-HGF)POF2-89572$$1G:(DE-HGF)POF2-89570$$2G:(DE-HGF)POF3-890$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x1 000151505 9131_ $$0G:(DE-HGF)POF3-572$$1G:(DE-HGF)POF3-570$$2G:(DE-HGF)POF3-500$$3G:(DE-HGF)POF3$$4G:(DE-HGF)POF$$aDE-HGF$$bKey Technologies$$lDecoding the Human Brain$$v(Dys-)function and Plasticity$$x0 000151505 9141_ $$y2014 000151505 915__ $$0StatID:(DE-HGF)0010$$2StatID$$aJCR/ISI refereed 000151505 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR 000151505 915__ $$0StatID:(DE-HGF)0111$$2StatID$$aWoS$$bScience Citation Index Expanded 000151505 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection 000151505 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bThomson Reuters Master Journal List 000151505 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS 000151505 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline 000151505 915__ $$0StatID:(DE-HGF)0310$$2StatID$$aDBCoverage$$bNCBI Molecular Biology Database 000151505 915__ $$0StatID:(DE-HGF)0400$$2StatID$$aAllianz-Lizenz / DFG 000151505 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz 000151505 9201_ $$0I:(DE-Juel1)INM-3-20090406$$kINM-3$$lKognitive Neurowissenschaften$$x0 000151505 980__ $$ajournal 000151505 980__ $$aVDB 000151505 980__ $$aI:(DE-Juel1)INM-3-20090406 000151505 980__ $$aUNRESTRICTED