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@ARTICLE{Fedosov:152169,
      author       = {Fedosov, Dmitry and Noguchi, Hiroshi and Gompper, Gerhard},
      title        = {{M}ultiscale modeling of blood flow: from single cells to
                      blood rheology},
      journal      = {Biomechanics and modeling in mechanobiology},
      volume       = {13},
      number       = {2},
      issn         = {1617-7940},
      address      = {Berlin},
      publisher    = {Springer},
      reportid     = {FZJ-2014-01949},
      pages        = {239-258},
      year         = {2014},
      abstract     = {Mesoscale simulations of blood flow, where the red blood
                      cells are described as deformable closed shells with a
                      membrane characterized by bending rigidity and stretching
                      elasticity, have made much progress in recent years to
                      predict the flow behavior of blood cells and other
                      components in various flows. To numerically investigate
                      blood flow and blood-related processes in complex
                      geometries, a highly efficient simulation technique for the
                      plasma and solutes is essential. In this review, we focus on
                      the behavior of single and several cells in shear and
                      microcapillary flows, the shear-thinning behavior of blood
                      and its relation to the blood cell structure and
                      interactions, margination of white blood cells and
                      platelets, and modeling hematologic diseases and disorders.
                      Comparisons of the simulation predictions with existing
                      experimental results are made whenever possible, and
                      generally very satisfactory agreement is obtained},
      cin          = {IAS-2 / ICS-2},
      ddc          = {570},
      cid          = {I:(DE-Juel1)IAS-2-20090406 / I:(DE-Juel1)ICS-2-20110106},
      pnm          = {451 - Soft Matter Composites (POF2-451)},
      pid          = {G:(DE-HGF)POF2-451},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000335722700002},
      doi          = {10.1007/s10237-013-0497-9},
      url          = {https://juser.fz-juelich.de/record/152169},
}