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000015250 0247_ $$2DOI$$a10.1093/cercor/bhr083
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000015250 084__ $$2WoS$$aNeurosciences
000015250 1001_ $$0P:(DE-Juel1)131693$$aLangner, R.$$b0$$uFZJ
000015250 245__ $$aModality-Specific Perceptual Expectations Selectively Modulate Baseline Activity in Auditory, Somatosensory, and Visual Cortices
000015250 260__ $$aOxford$$bOxford Univ. Press$$c2011
000015250 300__ $$a2850 - 2862
000015250 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article
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000015250 3367_ $$2BibTeX$$aARTICLE
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000015250 3367_ $$2DRIVER$$aarticle
000015250 440_0 $$01171$$aCerebral Cortex$$v21$$x1047-3211$$y12
000015250 500__ $$aDeutsche Forschungsgemeinschaft (IRTG 1328 to R. L., K. W., and S. B. E.); Human Brain Project (R01-MH074457-01A1 to S. B. E.); Initiative and Networking Fund of the Helmholtz Association within the Helmholtz Alliance on Systems Biology (Human Brain Model to S. B. E).
000015250 520__ $$aValid expectations are known to improve target detection, but the preparatory attentional mechanisms underlying this perceptual facilitation remain an open issue. Using functional magnetic resonance imaging, we show here that expecting auditory, tactile, or visual targets, in the absence of stimulation, selectively increased baseline activity in corresponding sensory cortices and decreased activity in irrelevant ones. Regardless of sensory modality, expectancy activated bilateral premotor and posterior parietal areas, supplementary motor area as well as right anterior insula and right middle frontal gyrus. The bilateral putamen was sensitive to the modality specificity of expectations during the unexpected omission of targets. Thus, across modalities, detection improvement arising from selectively directing attention to a sensory modality appears mediated through transient changes in pretarget activity. This flexible advance modulation of baseline activity in sensory cortices resolves ambiguities among previous studies unable to discriminate modality-specific preparatory activity from attentional modulation of stimulus processing. Our results agree with predictive-coding models, which suggest that these expectancy-related changes reflect top-down biases--presumably originating from the observed supramodal frontoparietal network--that modulate signal-detection sensitivity by differentially modifying background activity (i.e., noise level) in different input channels. The putamen appears to code omission-related Bayesian "surprise" that depends on the specificity of predictions.
000015250 536__ $$0G:(DE-Juel1)FUEK409$$2G:(DE-HGF)$$aFunktion und Dysfunktion des Nervensystems (FUEK409)$$cFUEK409$$x0
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000015250 588__ $$aDataset connected to Web of Science, Pubmed
000015250 65320 $$2Author$$afMRI
000015250 65320 $$2Author$$aintermodal attention
000015250 65320 $$2Author$$amultimodal stimulus anticipation
000015250 65320 $$2Author$$apredictive coding
000015250 65320 $$2Author$$asurprise
000015250 650_2 $$2MeSH$$aAnticipation, Psychological: physiology
000015250 650_2 $$2MeSH$$aAttention: physiology
000015250 650_2 $$2MeSH$$aAuditory Cortex: physiology
000015250 650_2 $$2MeSH$$aBrain Mapping
000015250 650_2 $$2MeSH$$aFemale
000015250 650_2 $$2MeSH$$aHumans
000015250 650_2 $$2MeSH$$aImage Interpretation, Computer-Assisted
000015250 650_2 $$2MeSH$$aMagnetic Resonance Imaging
000015250 650_2 $$2MeSH$$aMale
000015250 650_2 $$2MeSH$$aReaction Time: physiology
000015250 650_2 $$2MeSH$$aSomatosensory Cortex: physiology
000015250 650_2 $$2MeSH$$aVisual Cortex: physiology
000015250 650_2 $$2MeSH$$aYoung Adult
000015250 650_7 $$2WoSType$$aJ
000015250 7001_ $$0P:(DE-HGF)0$$aKellermann, T.$$b1
000015250 7001_ $$0P:(DE-Juel1)VDB131$$aBoers, F.$$b2$$uFZJ
000015250 7001_ $$0P:(DE-HGF)0$$aSturm, W.$$b3
000015250 7001_ $$0P:(DE-HGF)0$$aWillmes, K.$$b4
000015250 7001_ $$0P:(DE-Juel1)131678$$aEickhoff, S.B.$$b5$$uFZJ
000015250 773__ $$0PERI:(DE-600)1483485-6$$a10.1093/cercor/bhr083$$gVol. 21, p. 2850 - 2862$$p2850 - 2862$$q21<2850 - 2862$$tCerebral cortex$$v21$$x1047-3211$$y2011
000015250 8567_ $$uhttp://dx.doi.org/10.1093/cercor/bhr083
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000015250 9141_ $$y2011
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